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1、NitratemodulatesstemcelldynamicsinArabidopsisshootmeristemsthroughcytokininsaaa,baa,caBenoitLandrein,PauFormosa-Jordan,AliceMalivert,ChristophSchuster,CharlesW.Melnyk,WeibingYang,da,e,f,1a,g,1a,h,i,1ColinTurnbull,ElliotM.Meyerowitz,JamesC.W.Locke,andHenrikJönssonabSainsbur
2、yLaboratory,UniversityofCambridge,CB21LRCambridge,UnitedKingdom;ÉcoleNormaleSupérieuredeLyon,UniversitéClaudeBernardLyonI,cdUniversitédeLyon,69342Lyon,France;DepartmentofPlantBiology,SwedishUniversityofAgriculturalSciences,75651Uppsala,Sweden;DepartmentofeLifeSciences,Impe
3、rialCollegeLondon,SW72AZLondon,UnitedKingdom;HowardHughesMedicalInstitute,CaliforniaInstituteofTechnology,Pasadena,fgCA91125;DivisionofBiologyandBiologicalEngineering,CaliforniaInstituteofTechnology,Pasadena,CA91125;MicrosoftResearch,CB12FBCambridge,hUnitedKingdom;Computat
4、ionalBiologyandBiologicalPhysicsGroup,DepartmentofAstronomyandTheoreticalPhysics,LundUniversity,S-22100iLund,Sweden;andDepartmentofAppliedMathematicsandTheoreticalPhysics,UniversityofCambridge,CB30DZCambridge,UnitedKingdomContributedbyElliotM.Meyerowitz,December20,2017(sen
5、tforreviewOctober26,2017;reviewedbyAaronM.RashotteandRobertSablowski)Theshootapicalmeristem(SAM)isresponsibleforthegenerationofResultsalltheaerialpartsofplants.Givenitscriticalrole,dynamicalchangesPlantNutritionalStatusInfluencesShootMeristemFunction.WefirstinSAMactivitysh
6、ouldplayacentralroleintheadaptationofplantstudiedhowfixedlevelsofnutrientsaffectmeristemfunctionbyarchitecturetotheenvironment.Usingquantitativemicroscopy,growingplantsonsoilcontainingdiverselevelsofnutrients(SIgraftingexperiments,andgeneticperturbations,weconnecttheAppend
7、ix,TableS1).Toassessmeristemfunction,wemeasuredplantenvironmenttotheSAMbydescribingthemolecularmech-thesizeofthemeristem,theplastochronratio(afeaturethatisanismbywhichcytokininssignalthelevelofnutrientavailabilitytoinverselyproportionaltotheorganogenesisrateoftheSAM)theSAM
8、.Weshowthatasystemicsignalofcytokininprecursors(10),andthenumberofflowersproducedbythepri
