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1、KDOQICLINICALPRACTICEGUIDELINEFORHEMODIALYSISADEQUACY:2015UPDATEAbstractTheNationalKidneyFoundation’sKidneyDiseaseOutcomesQualityInitiative(KDOQI)hasprovidedevidence-basedguidelinesforallstagesofchronickidneydisease(CKD)andrelatedcomplicationssince1997.The2015u
2、pdateoftheKDOQIClinicalPracticeGuidelineforHemodialysisAdequacyisintendedtoassistpractitionerscaringforpatientsinpreparationforandduringhemodialysis.Theliteraturereviewedforthisupdateincludesclinicaltrialsandobservationalstudiespublishedbetween2000andMarch2014.
3、Newtopicsincludehigh-frequencyhemodialysisandrisks;prescriptionflexibilityininitiationtiming,frequency,duration,andultrafiltrationrate;andmoreemphasisonvolumeandbloodpressurecontrol.AppraisalofthequalityoftheevidenceandthestrengthofrecommendationsfollowedtheGradi
4、ngofRecommendationAssessment,Devel-opment,andEvaluation(GRADE)approach.Limitationsoftheevidencearediscussedandspecificsuggestionsareprovidedforfutureresearch.Keywords:Hemodialysis;ClinicalPracticeGuideline;hemodialysisprescription;hemodialysisfrequency;initiatio
5、n;adequacy;treatmenttime;hemofiltration;ureamodeling;evidence-basedrecommendation;KDOQI.Incitingthisdocument,thefollowingformatshouldbeused:NationalKidneyFoundation.KDOQIclinicalpracticeguidelineforhemodialysisadequacy:2015update.AmJKidneyDis.2015;66(5):884-930.
6、884AmJKidneyDis.2015;66(5):884-930WorkGroupMembershipWorkGroupChairsJohnT.Daugirdas,MDThomasA.Depner,MDUniversityofIllinoisCollegeofMedicineUniversityofCalifornia,DavisChicago,ILSacramento,CAWorkGroupMembersJulaInrig,MD,MHSDukeUniversityMedicalCenterYorbaLinda,
7、CARajnishMehrotra,MDUniversityofWashingtonDivisionofNephrology,HarborviewMedicalCenterSeattle,WAMichaelV.Rocco,MD,MSCEWakeForestSchoolofMedicineWinstonSalem,NCRitaS.Suri,MD,MSc,FRCPCUniversityofMontrealMontreal,QuebecDanielE.Weiner,MD,MSTuftsMedicalCenterBoston
8、,MAEvidenceReviewTeamUniversityofMinnesotaDepartmentofMedicineMinneapolisVACenterforChronicDiseaseOutcomesResearch,Minneapolis,MN,USANancyGreer,PhD,HealthScienceSpecialistAr
