Q-开关激光联合强脉冲光治疗黄褐斑临床疗效分析

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1、Vo1．21No．13July2010HAINANM匮DICALJOURNAL《海南医学)2010年第2l卷第l3期·论著·Q一开关激光联合强脉冲光治疗黄褐斑临床疗效分析肖和，杨志强，杨正文，刘勤，宋美，黎志中，俞晓岚(广州医学院第二附属医院整形外科，广东广州510260)【摘要】目的探讨和评价Q一开关激光联合强脉冲光(IPL)治疗黄褐斑的临床疗效和安全性。方法激光治疗组35例，采用MedliteQ一开关激光治疗6次，间隔1个月治疗一次；激光与强脉冲光联合治疗组42例，先用MedliteQ一开关激光治疗6次，间隔1个月

2、治疗一次，再用Lumenisone强脉冲光治疗5次，间隔1个月治疗一次；对照组12例，采用中药祛斑面膜治疗，每周1次，连续4周一个疗程，总共完成6个疗程。所有患者严格防晒，勿过度劳累。结果黄褐斑对照组治愈0例，显效3例(25．0o％)，总有效率为25．0o％；激光治疗组治愈6例(17。14％)，显效16例(45．71％)，总有效率为62．85％；激光与强脉冲光联合治疗组治愈10例(23．81％)，显效23例(54．76％)，总有效率为78．57％。激光治疗组和联合治疗组都取得了显著的疗效(P<0．05)。对照组红斑过敏

3、1例(8．33％)；激光治疗组色素沉着2例(5．71％)；联合治疗组色素沉着4例(9．52％)，色素减退2例(4．76％)，未见增生性瘢痕。结论Q一开关激光和强脉冲光(IPL)治疗黄褐斑安全、有效，副作用少，联合治疗能提高疗效。【关键词】黄褐斑；激光；强脉冲光；治疗【中图分类号】R758．42【文献标识码】A【文章编号】1003----6350(2010)13---015---04Clinicalefectoflaserandintensepulsedlightinthetreatmentofmelasmas．X3AO

4、He，GZhi—qiang，ⅣGZheng—wen，etaLDepartmentofPlasticandReconstructiveSurgery，SecondHospitalAfiliatedtoGuangzhouMedicalCollege，Guangzhou51026O，Guangdong，CHINA【Abstract】0bjec~veToexploreandevaluatethecurativeefectandsaftyoflaserandintensepulsedlightinthetreatmentofme

5、lasmas．Methods89patientswithmelasmaweretreated．35melasmaswereinitiallytreatedthO—switchedlaserwith1064nmwavelength，fouowedbysixtimesconsecutivetreatments，onceamonth．Other42melasmasfirstlyreceived6timesconsecutivetreatmentsofQ—switchedlaserwithlO64Iliawavelength．

6、tllenweretreatedby5timesconsecutivetreatmentswithIPLonceamortth．AndstillOtllertwelvemelasmaswereconsist．entofthecontrolteamreceived24timesconsecutivetreatmentsoftraditionalChinesemedicinefaeialmask，onceaweek．Allofpatientswerestrictwithsun—proof．ResultsThecurativ

7、eefectofthecontrolteam．thetreatmentteamoflaserandthetreatmentteamoflaserandIPLwere25％．62．85％and78．57％．respectively．Theside—efectswerealsoobserved．Erythemawas8．33％jnthecontrolteam．Hyperpigmentationwas5．71％and9．52％inthetreatmentteamofLaserandthetreatmentteamofLase

8、randIPL．HypopigraentationiS4．76％inthetreat．mentteamofLaserandIPL．HypertrophicscarWasnotfound．ConclusionLaserandIPLwereefectiveandsafeintreatmentofmelasmas．【Kwords】Mel