Prognostic value of myocardial perfusion and ventricular function in a Japanese multicenter cohort study (J-ACCESS) the first-year total events and hard events

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1、AnnNuclMed(2009)23:373–381DOI10.1007/s12149-009-0248-2ORIGINALARTICLEPrognosticvalueofmyocardialperfusionandventricularfunctioninaJapanesemulticentercohortstudy(J-ACCESS):thefirst-yeartotaleventsandhardeventsKenichiNakajimaÆHideoKusuokaÆShigeyukiNishimuraÆAkiraYamashinaÆTs

2、unehikoNishimuraReceived:27October2008/Accepted:19January2009/Publishedonline:14April2009ÓTheJapaneseSocietyofNuclearMedicine2009AbstractResultsDuringthe1-yearfollow-upperiod,263(6.5%)ObjectiveTodeterminetheprognosticvalueofmyocar-patientshadtotaleventscomprisingall-cause

3、death,non-dialischemia,functionandcoronaryriskfactorsontotalfatalmyocardialinfarction(MI),heartfailure,unstableandhardcardiaceventsusingmyocardialperfusionimag-angina,anginapectorisandcoronaryrevascularization.inginaJapanesepopulation.Cardiacdeathoccurredin23patients(0.6%

4、)andnon-fatalMethodsAprospectivecohortstudywasperformedinMIin11(0.3%).Amongpatientswithejectionfraction117Japanesehospitals,eachwithanuclearcardiology(EF)of45%andasummeddifferencescore(SDS)ofC2,facility.Atotalof4,031patientswithsuspectedorcon-18.7%(2.4%forcardiacdeathand

5、0.6%fornon-fatalMI)firmedischemicheartdiseasewereregistered.Thepatientsexperiencedtotaleventscomparedwith3.9%(0.3%forwerefollowedupforayeartoinvestigatetotalandhardcardiacdeathand0.2%fornon-fatalMI;P.0001)ofevents,andthosewhohadanyeventswerefollowedupforthosewithEFC45%an

6、dSDS2.Multivariateanalysis3yearstoevaluatesubsequenthardevents.Astress-restidentifiedEF,SDS,age,historyofrevascularizationandgatedmyocardialperfusionstudywasperformedwithdiabetesassignificantpredictorsofallevents,whilethe99mTc-tetrofosminusinggatedsingle-photonemissionsign

7、ificantpredictorswereageandEFforhardevents.computedtomography(SPECT)andanalyzedbysemi-Whenthepatientswhohadheartfailureinthefirstyearquantitativescores.werefollowedup,9of41(22.0%)experiencedcardiacdeathinthesubsequent3-yearfollow-upperiod.ConclusionsMyocardialischemiadefined

8、bySDSandK.Nakajima(&)ventricularfunctionwerethemainpredictorsoftotalDepartmentofNuclearMedicine,