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时间:2019-07-23
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1、94CalciumPhosphate,DibasicAnhydrous5Purac.Materialsafetydatasheet.No.2001/58/EC:PuracalPP,2612MeiY,ZhaoY.Barrierandmechanicalpropertiesofmilk-proteinbasedOctober2004.ediblefilmscontainingneutraceuticals.JAgricFoodChem2003;51:6SakateYetal.Characterizationofdehydrati
2、onandhydrationbehavior1914–1918.ofcalciumlactatepentahydrateanditsanhydrate.ColloidsSurfB13ShelefLA.Antimicrobialeffectsoflactates:areview.JFoodProt1994;Biointerfaces2005;46:135–141.57:444–450.7WongKK,SeckerD.Calciumandphosphateprecipitation–a14FoodChemicalsCodex,6
3、thedn.Bethesda,MD:UnitedStatesmedicationandfoodinteraction.CanJHospPharm1996;49:119.Pharmacopeia,2008;135.C8InskeepGCetal.Lacticacidfromcornsugar.Astaff-industrycollaborativereport.IndEngChem1952;44:1955–1966.20GeneralReferences9MaekawaAetal.Long-termtoxicity/carci
4、nogenicitystudyofcalcium—lactateinF344rats.FoodChemToxicol1991;29:589–594.10FDACodeofFederalRegulations.Directfoodsubstancesaffirmedas21Authorgenerallyrecognisedassafe–CalciumLactate.Title21,Section184:1207.WCook.11SakateYetal.Anovelwhitefilmforpharmaceuticalcoatin
5、gformedbyinteractionofcalciumlactatepentahydratewithhydroxypropyl22DateofRevisionmethylcellulose.IntJPharm2006;317:120–126.27February2009.CalciumPhosphate,DibasicAnhydrous1NonproprietaryNamesathigherpressurescanexhibitlaminationandcapping.ThisBP:AnhydrousCalciumHyd
6、rogenPhosphatephenomenoncanbeobservedwhenthematerialrepresentsasubstantialproportionoftheformulation,andisexacerbatedbytheJP:AnhydrousDibasicCalciumPhosphateuseofdeepconcavetooling.ThisphenomenonalsoappearstobePhEur:CalciumHydrogenPhosphate,Anhydrousindependentofra
7、teofcompaction.USP:AnhydrousDibasicCalciumPhosphateAnhydrousdibasiccalciumphosphateisabrasiveandalubricantisrequiredfortableting,forexample1%w/wmagnesiumstearate2Synonymsor1%w/wsodiumstearylfumarate.Twoparticle-sizegradesofanhydrousdibasiccalciumphosphateA-TAB;calc
8、iihydrogenophosphasanhydricus;calciummonohy-areusedinthepharmaceuticalindustry.Milledmaterialistypicallydrogenphosphate;calciumorthophosphate;Di-
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