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1、DepartmentofInfectiousDiseasesThirdhospital,SunYet-senUniversityPro.fGaozhiliangGENERALPRICIPLESOFINFECTIOUSDISEASES1SINGNIFECANCEANDIMPORTANCE2HistoryreviewIn14thcentury,PlagueinEuropean,20millionpeopledeath；In17~18thcentury,smallboxinEuropean，150millionpeopledeath；In1
2、918,fluintheworldwide，40millionpeopledeath。3In1905,NobelgainerofphysiologyandmedicineawardRobertKoch(Germany)Kochdiscoveredtubculosisbacilii4In1945,NobelgainerofphysiologyandmedicineawardAlexanderFleming(Scotland)In1928年，FlemingDiscorveredPenicillinIntoantibioticsera5WH
3、Oreports：Among52millionofdeathintheworldwideannually,17million(32%)ofdeathfrominfectiousdiseasesandparasiteIndevelopingcountry，ahalfofdeathbyinfectiousdiseases；About15millionofdeathbyinfectiousdiseasesperhourintheworldwide，mostoccurredindevelopingcountry。6PatternofInfec
4、tioninDevelopedCountriesIn20thcentury,fallintheincidenceofcommunicablediseasesindevelopedcountriesduetofactorssuchas:Immunizationantimicrobialchemotherapyimprovednutritionandbettersanitationandhousing.7Re-emergenceofoldinfectiousdisease◆(Tuberculosis)◆(Viralhepatitis)◆(
5、Sexuallytransmitteddiseases)◆others:cholera、charcoal8Re-emergenceofoldinfectiousdisease2milliondeathofTBintheworldwideannually7～8millioninfectedbyTBintheworldwideannuallyMarch24,forWorldTBDay9EmerginginfectiousdiseasesWHOinformationnear30years,about30kindsofinfectiousdi
6、seasesdiscoveredintheworldwide“Emerginginfectiousdiseases”10Emerginginfectiousdiseases40millionofHIV/AIDScasesworldwideHIVinfectionrates:11cases/minute16000persons/perday6millionpersons/annually。95%indevelopingcountryMaximalnation:Africa,infectionrateabout10%Dec.1forWor
7、ldAIDSDay11EmerginginfectiousdiseasesSARS（SARS—CoV）From2002.11.16to2003.7，SARSspreaded6continent,32countries，casesof8437，deathof916Inchina,casesof5327，deathof349SARS:mostseriousemerginginfectiousdiseasesin21century12EmerginginfectiousdiseasesAvianinfluenzaH5N1virusH1N1V
8、IRUS13AntibioticsAntibiotics,withinthelast60years,ResultedinthecureofmanypreviouslylethalinfectionsOnlyseveral
