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1、THEJERUSALEM-HARVARDLECTURESSponsoredbytheHebrewUniversityofJerusalemandHarvardUniversityPress[Toviewthisimage,refertotheprintversionofthistitle.]HOWTOWINTHENOBELPRIZEAnUnexpectedLifeinScienceJ.MICHAELBISHOPHarvardUniversityPressCambridge,MassachusettsLondon,England2003Copyright©2003bythePresident
2、andFellowsofHarvardCollegeAllrightsreservedPrintedintheUnitedStatesofAmericaFirstHarvardUniversityPresspaperbackedition,2004Page257constitutesanextensionofthecopyrightpage.Frontispiece:WilliamBlake,Newton,1795.©Tate,London2002.LibraryofCongressCataloging-in-PublicationDataBishop,J.Michael,1936Howto
3、wintheNobelPrize:anunexpectedlifeinscience/J.MichaelBishop.p.cm.(TheJerusalem-Harvardlectures)Includesbibliographicalreferencesandindex.ISBN0-674-00880-4(alk.paper)ISBN0-674-01625-4(pbk.)1.Bishop,J.Michael,19362.MedicalscientistsUnitedStatesBiography.3.Oncogenes.4.NobelPrizes.I.Title.II.Series.RC26
4、8.42.B572003610.92dc212002192234[B]TothememoryofmymotherandfatherContentsListofIllustrationsixPrefacexi1.ThePhoneCall12.AccidentalScientist373.PeopleandPestilence774.OpeningtheBlackBoxofCancer1335.ParadoxicalStrife181Notes231Credits257Index259IllustrationsNewtonbyWilliamBlakefrontispieceArtbyTomMa
5、rioni1NobelAttirebyJamieSimon4BillboardnearGettysburg,Pennsylvania,October198911TheBishopfamilywiththeKingandQueenofSweden,December10,198916ItwasjustthatonetimethatyouwontheNobelPrize,wasntit,dear?byMortGerberg25PotentialSurfaceofDensitybyTerryWinters29Nobelwager33DansedeBiochemistebyLarsBo37Unfocu
6、sed43LaboratoryStillLifeNo.4byTonyCragg46Poliovirus50LeonardosLamentbySidneyHarris59Twelveyearson74EpidemicbyAlfredKubin77SyphilisbyKatheKollwitz84Streptococci87Bacterialcolonies93Anthrax95Microbes97TheSurgicalClinicofProfessorGrossbyThomasEakins114Man,ControlleroftheUniverse(detail)byDiegoRivera13
7、3Cells136Expressionofthegeneticprograminvertebratecells143Cancerwasproduced.ProudlyIwalkafewstepsbyKatsusaburoYamagiwa149Chromosomesandcancer155Normalandmalignantcellsasviewedwithanelectronmicroscope161Agen
