不同剂量赤芍对解毒化瘀汤治疗慢性乙型重型肝炎疗效影响

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1、TheCurativeEffectonDifferentDosageChishaoamongJieduhuayuDecoctionforTreatingChronicBTypeSevereHepatitisPostgraduate:LiuBiTuor:ProfessorXiongYanABSTRACTObjective:ByobservingthecurativeeffectonthreedifferentdosageChishaoamongJieduhuayudecoction(JDHYD)fortr

2、eatingchronicBtypeseverehepatitis,objectiveistofurtherexploretheChishaooptimaldosageforprovidingclinicalpractice.Methods:Pick60chronicseverehepatitisBearlyandmid-termpatients.Accordingtothesequenceofadmission,theywererandomlydividedintothreegroups,eachgr

3、oup20.Onthebasisofthecombinedtherapy,3groupstakeJDHYDatthesametime.Thatis,thefirstgroupisgivenJDHYD(Chishaodosage30g),andthesecondgivenJDHYD(Chishaodosage60g),andthethirdgivenJDHYD(Chishaodosage120g),double-blindadministration.Thedecoctionisgiventwobagse

4、achday,eachbag125ml.Thetreatmentis4weeks.TheliverfunctiontestandPTAshouldbetestedbyvenousbloodbeforetakingmedicine.Thenaboveindicatorsshouldbetestedfor4weeks.Atlast,theeffectshouldbecomparedonthreedifferentdosagesofChishaoamongJDHYDfortreatingchronicBtyp

5、eseverehepatitis.Results:1.Accumulatethevauleofsymptomsandsigns:ithassignificantdifferencesstatisticallybycomparingthreevauleaftertreatingthreeweeks(p＜0.05).Thereisnosignificantdifferencestatisticallybetween60ggroupand120ggroup（p＞0.05）,buttheyarebothadva

6、ntageto30ggroup(p＜0.05).2.Serumtotalbilirubin(TBIL):thereisnosignificantdifferencestatisticallybetween60ggroupand120ggroupaftertreatingfourweeks（p＞0.05）,buttheyarebothbetterthan30ggrouponreducingjaundice(p＜0.05).3.Serumalbumin(ALB):thereisnosignificantdi

7、fferencestatisticallybetween60ggroupand120ggroupaftertreatingfourweeks（p＞0.05）,buttheyarebothbetterthan30ggrouponupgradingalbumin(p＜0.05).4.Alanineaminotransferase(ALT):thereisnosignificantdifferencestatisticallybetween60ggroupand120ggroupaftertreatingfo

8、urweeks（p＞0.05）,buttheyarebothbetterthan30ggrouponloweringtransaminase.5.Prothrombinactivity(PTA):thereisnosignificantdifferencestatisticallybetween60ggroupand120ggroupaftertreatingfourweeks（p＞0.05）,buttheyarebothbettertha