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ID:39111081
大小:3.02 MB
页数:63页
时间:2019-06-25
《Trophinin2ctastin2cbystin在人子宫内膜、胚胎细胞与胎盘绒毛上的表达与其在胚胎着床与胎盘形成过程中的重要作用》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、增生期未见表达(P2、体滋养层细胞的细胞浆及细胞膜;于妊娠10w的胎盘绒毛合体滋养层细胞上,Uophinin,tasfi玛bysfin表达显著减弱(P3、是某些类型不孕的重要原因之一。2.Tmphinin蛋白分子在人囊胚细胞上的表达为胚胎与分泌中期子宫内膜的双向作用提供了可供相互识别的分子,这种互为配、受体的新型作用模式可能是胚胎着床的重要机制之一。3.Tmphinin,msfin,bysttn粘附分子复合体在不同时期的绒毛组织细胞上表达呈现不同的特点,与胎盘基本形成时消失。提示其可能与胎盘形成有关;米非司酮影响滋养层细胞上的trophinin,bystin,tastin蛋白分子的表达,提示其可能参与了流产的发生过程。f关键词:粘附分子复合体;Bopbinjn,las村n,.b狰一子宫内膜;暑床x不孕;滋养层;胎盘;米非司酮4、;胚胎;囊胚、ObjectivesAbstract1.ToinvestigatetheexpressionofanovelcelladhesionmoleculeCOmplexwhichiscomposedoftrophinin,tastin,andbystininhumanendometriurn,anditsrelationshipwithsomesortsofinferdlity.2.TodetecttheexpressionofIrophinininhumanembryoanditscharacters.3.Tostudytheroleofthecomplexonh5、umanplacentafionandtheinfluenceofMifepristoneontheexpressionofthecomplexinhumanvilloustrophoblast.methods1.ImmunohistochemistrytechniquewimspecificmonoclonalantibodyWflSappliedtoinvestigatetherelationshipbetweenanovdceUadhesionmolecularcomplexwhichiscomposedoftrophinin,t8妣andbystinandinfer6、tilitybydetectingtheexpressionofthecomplexinnormalcyclingendometriumandthedifferentcesbetweenthenormalandtheinfertility.2.IIFtechniquewithspecificmonoclonalantibodywasappliedtoinvestigatetheexpressionoftrophynininhumanblastomereandblastocyst,whichWaSgainedwiththesequentialcultureinvitro.3.7、Immunohistochemistxytechniquewinlspecificmonoclonalantibody诵邵appliedtodetecttheexpressionofthecomplexinhumanplacentavilliofdifferentphasesofpregnancy,meanwhilethedifferenceoftheexpressionoftrophinin,tastinandbystininhumanplacentafrom14sugicalabortionsbynegativ
2、体滋养层细胞的细胞浆及细胞膜;于妊娠10w的胎盘绒毛合体滋养层细胞上,Uophinin,tasfi玛bysfin表达显著减弱(P3、是某些类型不孕的重要原因之一。2.Tmphinin蛋白分子在人囊胚细胞上的表达为胚胎与分泌中期子宫内膜的双向作用提供了可供相互识别的分子,这种互为配、受体的新型作用模式可能是胚胎着床的重要机制之一。3.Tmphinin,msfin,bysttn粘附分子复合体在不同时期的绒毛组织细胞上表达呈现不同的特点,与胎盘基本形成时消失。提示其可能与胎盘形成有关;米非司酮影响滋养层细胞上的trophinin,bystin,tastin蛋白分子的表达,提示其可能参与了流产的发生过程。f关键词:粘附分子复合体;Bopbinjn,las村n,.b狰一子宫内膜;暑床x不孕;滋养层;胎盘;米非司酮4、;胚胎;囊胚、ObjectivesAbstract1.ToinvestigatetheexpressionofanovelcelladhesionmoleculeCOmplexwhichiscomposedoftrophinin,tastin,andbystininhumanendometriurn,anditsrelationshipwithsomesortsofinferdlity.2.TodetecttheexpressionofIrophinininhumanembryoanditscharacters.3.Tostudytheroleofthecomplexonh5、umanplacentafionandtheinfluenceofMifepristoneontheexpressionofthecomplexinhumanvilloustrophoblast.methods1.ImmunohistochemistrytechniquewimspecificmonoclonalantibodyWflSappliedtoinvestigatetherelationshipbetweenanovdceUadhesionmolecularcomplexwhichiscomposedoftrophinin,t8妣andbystinandinfer6、tilitybydetectingtheexpressionofthecomplexinnormalcyclingendometriumandthedifferentcesbetweenthenormalandtheinfertility.2.IIFtechniquewithspecificmonoclonalantibodywasappliedtoinvestigatetheexpressionoftrophynininhumanblastomereandblastocyst,whichWaSgainedwiththesequentialcultureinvitro.3.7、Immunohistochemistxytechniquewinlspecificmonoclonalantibody诵邵appliedtodetecttheexpressionofthecomplexinhumanplacentavilliofdifferentphasesofpregnancy,meanwhilethedifferenceoftheexpressionoftrophinin,tastinandbystininhumanplacentafrom14sugicalabortionsbynegativ
3、是某些类型不孕的重要原因之一。2.Tmphinin蛋白分子在人囊胚细胞上的表达为胚胎与分泌中期子宫内膜的双向作用提供了可供相互识别的分子,这种互为配、受体的新型作用模式可能是胚胎着床的重要机制之一。3.Tmphinin,msfin,bysttn粘附分子复合体在不同时期的绒毛组织细胞上表达呈现不同的特点,与胎盘基本形成时消失。提示其可能与胎盘形成有关;米非司酮影响滋养层细胞上的trophinin,bystin,tastin蛋白分子的表达,提示其可能参与了流产的发生过程。f关键词:粘附分子复合体;Bopbinjn,las村n,.b狰一子宫内膜;暑床x不孕;滋养层;胎盘;米非司酮
4、;胚胎;囊胚、ObjectivesAbstract1.ToinvestigatetheexpressionofanovelcelladhesionmoleculeCOmplexwhichiscomposedoftrophinin,tastin,andbystininhumanendometriurn,anditsrelationshipwithsomesortsofinferdlity.2.TodetecttheexpressionofIrophinininhumanembryoanditscharacters.3.Tostudytheroleofthecomplexonh
5、umanplacentafionandtheinfluenceofMifepristoneontheexpressionofthecomplexinhumanvilloustrophoblast.methods1.ImmunohistochemistrytechniquewimspecificmonoclonalantibodyWflSappliedtoinvestigatetherelationshipbetweenanovdceUadhesionmolecularcomplexwhichiscomposedoftrophinin,t8妣andbystinandinfer
6、tilitybydetectingtheexpressionofthecomplexinnormalcyclingendometriumandthedifferentcesbetweenthenormalandtheinfertility.2.IIFtechniquewithspecificmonoclonalantibodywasappliedtoinvestigatetheexpressionoftrophynininhumanblastomereandblastocyst,whichWaSgainedwiththesequentialcultureinvitro.3.
7、Immunohistochemistxytechniquewinlspecificmonoclonalantibody诵邵appliedtodetecttheexpressionofthecomplexinhumanplacentavilliofdifferentphasesofpregnancy,meanwhilethedifferenceoftheexpressionoftrophinin,tastinandbystininhumanplacentafrom14sugicalabortionsbynegativ
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