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时间:2017-11-25
《60岁以上老年继发孔型房间隔缺损的治疗策略(附139例临床分析)》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、128心肺血管病杂志2010年3月第29卷第2期JournalofCardiovascular&PulmonaryDiseases,丛rc!:!:DOI:10.3969/j.issn.1007-5062.2010.02.015l临床论著·6O岁以上老年继发孔型房间隔缺损的治疗策略(附139例临床分析)迟立群张健群孔睛宇肖巍(摘要]目的:介绍老年继发孔型房间隔缺损(ASD)的几种治疗方法,并分析其治疗效果。方法:自2002年1月至2009年6月,我院收治的139例60岁以上的老年继发孑L型ASD病例。其中43例行经导管房缺封堵术;21例行微创经胸房缺封堵术;55例行体外循环下房缺
2、修补术;20例因各种原因未行手术,给予药物保守治疗。结果:导管封堵组、经胸封堵组、和手术修补组患者均无死亡。术后远期随访导管封堵组,1例术后第4年死于脑出血。其余2组术后远期随访无死亡。房缺闭合术后心功能较术前明显改善,术后早期复查超声心动图均无残余分流,右心房、右心室明显缩小,肺动脉压力明显降低。保守治疗组,随访病例共有8例死亡。其中4例死于心力衰竭(心衰),1例死于心衰合并尿毒症,1例死于脑出血,1例死于呼吸衰竭,1例死因不详。结论:高龄本身并非老年房间隔缺损手术禁忌,老年患者通过封堵器或手术闭合房缺仍可以重构右心房、右心室,降低肺动脉压,显著改善心功能。3种闭合方法各有优
3、缺点,应根据具体情况选择手术方式。[关键词]老年;房间隔缺损;微创手术;导管封堵术;心脏外科手术[中图分类号]R541.1[文献标识码]A[文章编号]1007-5062(2010)02-128-04Strategyoftreatmentforsecundumatrialseptaldefectinpatientsolderthan60yearsofageCHILiqun,ZHANGJianqun,KONGQingyu,XIAOWeiDepartmentofCardiacSurgery,CapitalMedicalUniversi-tyaffiliated8eijingAnzhe
4、nHospital,BeifingInstituteofHeart,LungandBloodVesselDiseases,Belting100029,China[Abstract]Objective:Toreviewandanalyzetheresultsofseveralwaysfortreatmentforatrialseptaldefectintheelderlyinasingleinstitution.Methods:139patientsagedfrom60to89yearsold(mean66.32±5.33)fromJanuary2002throughJune20
5、09,formthecohortofthisstudy.Amongthem,43casesunderwenttranseatheterclosureoftheirASDswithoccluderdevice;21casesunderwentminimallyinvasiveper—thoracicclosureoftheirASDswithoceluderdevice;55casesunderwentASDrepairoperationwitheardiopulmonaryby—pass;20casesdidnotundergoanyoperationexceptmedical
6、treatmentforkindsofreasons.Results:Results:Therewerenooperativedeathinallthosepatientswhounderwenttranscatheterclosure,trans—thoracicclosure,andsurgicalrepairofASD.Atthetimeoffollow—up,allthesepatientswerestillaliveexcept1diedfromcere—bralhaemorrhage4yearsafterthetranscatheterclosureofASD.Th
7、eheanfunctionwasmuchbetterthanpre.operationinthosepatients.(InNYHAClass,pre-closure3.08±0.23s.post—closure2.14±0.19,n=117,P<0.O1)Post—operativeultrasoundshowednoresidualshuntinthosecases,boththerightatrialandtherightventricularreducedsignificantly[
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