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1、StatisticsforBiologyandHealthSeriesM.GailK.KrickebergJ.SametA.TsiatisW.WongForothertitlespublishedinthisseries,gotohttp://www.springer.com/series/2848“Thispageleftintentionallyblank.”KarlW.Broman·SaunakSen´AGuidetoQTLMappingwithR/qtl123KarlW.BromanSaunakSen´DepartmentofBi
2、ostatisticsDepartmentofEpidemiology&Biostatistics&MedicalInformaticsUniversityofCalifornia,SanFranciscoUniversityofWisconsinMadison185BerrySt.,Suite57001300UniversityAve.SanFrancisco,CA94107-1762Madison,WI53706-1510USAUSAsen@biostat.ucsf.edukbroman@biostat.wisc.eduPortion
3、softheauthorsarticlespublishedinGeneticsarereprintedwithpermissionoftheGeneticsSocietyofAmerica.RLinuxisaregisteredtrademarkofLinusTorvalds.TMTMGoogleandGoogleGroupsaretrademarksofGoogleInc.RRRMicrosoft,Windows,andExcelareregisteredtrademarksofMicrosoftCorporation.R
4、RRMac,MacOS,andMacintoshareregisteredtrademarksofAppleComputer,Inc.RUNIXisaregisteredtrademarkofTheOpenGroup.ISSN1431-8776ISBN978-0-387-92124-2e-ISBN978-0-387-92125-9DOI10.1007/978-0-387-92125-9SpringerDordrechtHeidelbergLondonNewYorkLibraryofCongressControlNumber:20099
5、29238cSpringerScience+BusinessMedia,LLC2009Allrightsreserved.Thisworkmaynotbetranslatedorcopiedinwholeorinpartwithoutthewrittenpermissionofthepublisher(SpringerScience+BusinessMedia,LLC,233SpringStreet,NewYork,NY10013,USA),exceptforbriefexcerptsinconnectionwithreviewsors
6、cholarlyanalysis.Useinconnectionwithanyformofinformationstorageandretrieval,electronicadaptation,computersoftware,orbysimilarordissimilarmethodologynowknownorhereafterdevelopedisforbidden.Theuseinthispublicationoftradenames,trademarks,servicemarks,andsimilarterms,evenifth
7、eyarenotidentifiedassuch,isnottobetakenasanexpressionofopinionastowhetherornottheyaresubjecttoproprietaryrights.Printedonacid-freepaperSpringerispartofSpringerScience+BusinessMedia(www.springer.com)ToAimeeandSuheeta“Thispageleftintentionallyblank.”PrefaceQTLarequantitative
8、traitloci:geneticlocithatcontributetovariationinaquantitativetrait.QTLmappingistheefforttoidentif