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1、ComputersandElectronicsinAgriculture30(2001)205±218www.elsevier.com:locate:compagBiosensorsdevelopmentsandpotentialapplicationsintheagriculturaldiagnosissectorIbtisamE.Tothill*Cran®eldBiotechnologyCentre,Cran®eldUni6ersity,Cran®eld,Bedfordshire,MK430AL,UKAbstractTherehasbeenaphe
2、nomenalgrowthinthe®eldofbiosensordevelopmentinrecentyearswithemergingapplicationsinawiderangeofdisciplines,includingmedicalanalysis,foodandtheenvironment.Theincreaseinthenumberofanalytesrequiringmonitoringandothersthatrequirecontrol,andtheneedforhighsensitivity,speed,andaccuracy
3、ofanalyticalmeasurementshavestimulatedconsiderableinterestindevelopingsensorsasdiagnosticstools.Arangeofmoleculeswithbiorecognitionpowersareavailablenaturallysuchasantibodies,enzymes,cellreceptorsandnucleicacidsandareusedasthesensingreceptorsinbiosensors.Thecombinedapproachesofc
4、omputer(molecular)modellingandcombinatorialsynthesisormolecularlyimprintedpolymersareundertakentodayasanewmethodtoproducesyntheticreceptorsthatcanbeusedinsensordevelopment.Awiderangeoftransducersisalsofeasibletoful®ltherapidmonitoringneedsofthediagnosticmarket.Biosensorscanalsob
5、eincorporatedintosimple-to-useinstrumentsasanon-linemonitoringdeviceoraone-shotsensor.Thispaperdealswithrecentdevelopmentsinbiosensorsandtheirpotentialuseintheagriculturaldiagnosticmarket.©2001ElsevierScienceB.V.Allrightsreserved.Keywords:Biosensors;Af®nitysensors;Electronicnose
6、;Foodanalysis;Environment1.IntroductionRecentyearshaveseenwatercompanies,foodmanufacturersandfarmersunderincreasingpressure,bothfromconsumersandlegislation.Thisistoprovidelifeessentialentities,suchaswater,airandfoodwhicharehighinquality,freefrom*Tel.:44-1234-754131;fax:44-1234
7、-750907.E-mailaddress:i.tothill@cran®eld.ac.uk(I.E.Tothill).0168-1699:01:$-seefrontmatter©2001ElsevierScienceB.V.Allrightsreserved.PII:S0168-1699(00)00165-4206I.E.Tothill:ComputersandElectronicsinAgriculture30(2001)205±218pollutingcompoundsandchemicalresiduesandaccurateinnutriti
8、onalvalueinthecaseoffood.Theincreaseinthenumber