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1、FacilitateInsightbyNon-InvasiveBrainStimulationRichardP.Chi,AllanW.Snyder*CentrefortheMind,UniversityofSydney,Sydney,AustraliaAbstractOurexperiencescanblindus.Oncewehavelearnedtosolveproblemsbyonemethod,weoftenhavedifficultiesingeneratingsolutionsinvolvingadifferentkindofinsight.
2、Yetthereisevidencethatpeoplewithbrainlesionsaresometimesmoreresistanttothisso-calledmentalseteffect.Thisinspiredustoinvestigatewhetherthementalseteffectcanbereducedbynon-invasivebrainstimulation.60healthyright-handedparticipantswereaskedtotakeaninsightproblemsolvingtaskwhilerecei
3、vingtranscranialdirectcurrentstimulation(tDCS)totheanteriortemporallobes(ATL).Only20%ofparticipantssolvedaninsightproblemwithshamstimulation(control),whereas3timesasmanyparticipantsdidso(p=0.011)withcathodalstimulation(decreasedexcitability)oftheleftATLtogetherwithanodalstimulati
4、on(increasedexcitability)oftherightATL.Wefoundhemisphericdifferencesinthatastimulationmontageinvolvingtheoppositepolaritiesdidnotfacilitateperformance.OurfindingsareconsistentwiththetheorythatinhibitiontotheleftATLcanleadtoacognitivestylethatislessinfluencedbymentaltemplatesandth
5、attherightATLmaybeassociatedwithinsightornovelmeaning.Furtherstudiesincludingneurophysiologicalimagingareneededtoelucidatethespecificmechanismsleadingtotheenhancement.Citation:ChiRP,SnyderAW(2011)FacilitateInsightbyNon-InvasiveBrainStimulation.PLoSONE6(2):e16655.doi:10.1371/journ
6、al.pone.0016655Editor:DorothyBishop,UniversityofOxford,UnitedKingdomReceivedAugust17,2010;AcceptedJanuary10,2011;PublishedFebruary2,2011Copyright:ß2011Chi,Snyder.Thisisanopen-accessarticledistributedunderthetermsoftheCreativeCommonsAttributionLicense,whichpermitsunrestricteduse,d
7、istribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Funding:Theauthorshavenosupportorfundingtoreport.CompetingInterests:Theauthorshavedeclaredthatnocompetinginterestsexist.*E-mail:allan@centreforthemind.comIntroductiondisinhibitingcertainareasofth
8、ebrain?Toexplorethispossibility,weusedtr
