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ID:37577600
大小:223.30 KB
页数:27页
时间:2019-05-25
《class13 Regression Analysis of Correlated Data-new-f2008》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、TheRegressionAnalysisofCorrelatedDataTherearemanysituationsthatresultinsamplesthatarenotmadeupofindependentobservations•Familydata:Wecanexpectthatsubjectsinthesamefamilywillhaveobservationsthataremorealikewhencomparedtoeachotherthanwhencomparedtosubjectsinotherfamilies.•Datacollectedusingnon-
2、randomsampling:Whenusingasamplingschemethatselectsseveralhospitalsfromwhichsubjectswillberecruited,subjectsatthesamehospitalwillshareunmeasuredcharacteristicsthatwouldnothappenifsubjectswereselectedrandomlyfromthegeneralpopulation.•Repeatedmeasures:Whentakingrepeatedmeasurementsfromsubjects,o
3、bservationsthatarefromthesamesubjectwilltendtobemorealikethanwhencomparedtoothersubjectsobservations.Repeatedobservationscloserintimefromthesamesubjectmayalsobemorealikethanthosefurtherapartintime.2ConsequencesofNon-IndependentDataConsiderthisexperiment:•Youattendaconventionforidenticaltriple
4、tsthathas1,000setsofidenticaltriplets.•Youdecideyouhavetimetotake1,000systolicbloodpressuremeasurements.Youcaneither:1.Collectbloodpressuresfromallmembersof333-1/3setsoftripletsor,2.Takeonemeasurefromeachofthe1,000sets.IfyouwantaproperestimateofSBPattheconvention,areyoubetteroffdoing1or2?•Ifm
5、embersofatriplettendtohavesimilarbloodpressures,yougetlittleadditionalinformationbymeasuringmorethanonememberofasibship.•Thetotalinformationcontentofyourdatawillbereducedifyoudon’thaveindependentobservations.•Thestandarderrorsonyourestimateswillbetoosmallifyoudon’taccountforthecorrelations–yo
6、urdataisnotasgoodasyouthink!3Situation#2:SleepHoursinMenandWomen•Youaretestingthehypothesisthatmothersandfathersofnewbornswillgetsignificantlydifferenthoursofsleep,whereyoubelievethatmenwillsleepmorethanwomen.•Youcandothestudytwoways:1.Youcollect50couplesandcalculatethedifferenceinsleephoursb
7、etweenthemotherandfatherofanewborn.Isthisdifferencesignificantlydifferentfromzero?[pairedt-testwith50pairs].2.Youaccumulate50mothersand50fathersofnewborns,withnoattempttorecruitcouples.Youthencalculatethemeannumberofhoursofsleepinmothersandin
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