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1、CCaarrootitiddSStetenntitinnggEEqquuiippmmeennttaannddTTeecchhnniiqquueeRobertM.Bersin,MDFACCFSCAIDirector,EndovascularServicesandClinicalResearchSeattleCardiologyCardiovascularConsultantsofWashingtonSeattle,WashingtonCardiovascularConsultantsofWashingtonDisclosureInformationTTee
2、cchhnniiqquueeoofCfCaarrootitiddSStetenntitinnggRobertM.BersinMD,FSCAIThefollowingrelationshipsexistrelatedtothispresentation:NameofCompany:BostonScientificAB,C,GS,P,SBAB:AdvisoryBoardNameofCompany:Bristol-MyersSquibbC,SBC:ConsultingRelationshipNameofCompany:CordisEndovascularAB,
3、C,EI,P,SB,SEEI:EquityInterestNameofCompany:E.ILillyC,SBGS:GrantSupportNameofCompany:ev3PNameofCompany:GuidantCorporationC,PP:ProctororTrainingCourseSponsorshipsNameofCompany:TheMedicinesCompanySBSB:SpeakersBureauNameofCompany:Sanofi-AventisC,SBSE:SpouseEmployeeNameofCompany:Vascu
4、larArchitectsSOSO:StockOptionsorPositionsNameofCompany:VascularSolutionsAB,C,SOOfflabeluseofproductswillbediscussedinthispresentation:investigationalcarotidstentsystemsRMBersinSCAICoreCurriculuminCarotidStenting2006CarotidStentTrialMedicationsACTI,ARCHeR,BEACH,CABERNET,CREATE,CRE
5、ST,MAVERiCK,SAPPHIRE,SECuRITYMedicationPre-DayofPost-Post-ProcedureProcedureProcedure!Procedure2-3days30days>30daysAspirin81-650mg81-650mg81-650mg81-325mgindefinitelyClopidogrel75mg300-450mg475mgtwotoNotrequiredhrspriorfourweeksTiclopidine250mgBID250mgBID250mgBIDNottwoweeksrecomm
6、endedHeparinNA70U/KgACTAsneededNA250-300secforthrombus,WarfarinRxRMBersinSCAICoreCurriculuminCarotidStenting2006FatalCarotidStentThrombosisLLaacckkooffCCoommbbiinnaattiioonnAAnnttiippllaatteelleettTThheerraappyyIntraproceduralASAOnly72HrsPost-StentNoAntiplateletRMBersinSCAICoreCu
7、rriculuminCarotidStenting2005ChaturvediSetalStroke2001;32:2700-0230-DayTotalStrokeinU.S.CarotidStentingHighRiskRegistries1086.95.65.864.5Patients(%)4.04.243.420CABERNETMAVErICBEACHCREATESAPPHIREARCHeR2SECuRITY(TCT2004)(TCT2004)(TCT2004)(TCT2004)(AHA2002)(ACC2003)(TCT2003)RMBersin
8、SCAICoreCurriculuminCarotidStenting2006E