丹莪妇康煎膏联合达菲林治疗子宫内膜异位症术后疗效观察

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1、丹莪妇康煎膏联合达菲林治疗子宫内膜异位症术后疗效观察【摘要】目的：观察丹莪妇康煎膏联合达菲林治疗子宫内膜异位症(EMs)术后的临床疗效。方法：子宫内膜异位症患者120例,经腹腔镜下行非根治性手术治疗，术后随机分为治疗组62例，对照组58例。治疗组给予达菲林肌肉注射，28天1次，共3次，同时口服丹莪妇康煎膏6个月；对照组仅给予达菲林肌肉注射，28天1次，共6次。比较两组术后的疼痛缓解率、复发率、妊娠率、药物不良反应及治疗成本。结果：120例中，随访118例，随访率98.3%（118/120）；治疗组和对照组术后疼痛缓解率分别为96

2、.7%、96.6%，复发率分别为1.67%、1.72%，妊娠率分别为58.3%、55.6%，两组疗效比较，差异无统计学意义（P>0.05）。但两组用药后不良反应比较，治疗组明显低于对照组（P<0.05）；治疗组治疗成本明显低于对照组(P＜0.01)。结论：子宫内膜异位症腹腔镜术后应用丹莪妇康煎膏联合达菲林治疗安全、有效，且成本低。【关键词】子宫内膜异位症腹腔镜手术后达菲林丹莪妇康煎膏Dan’eFukangJiangaoCombinedwithDipherelineintheTreatmentofEndometrios

3、isPost-operationCHENWenzeng.ZhejiangProvinceHospitaloftheIntegrationofTraditionalChineseandWesternMedicine,Hangzhou(310003),ChinaAbstractObjective:Tostudytheeffectsofintegrativemedicineonthetreatmentofendometriosispost-operation.Methods:Atotalof120patientsfromSeptemb

4、er2007toFebruary2009whohadsurgeriesonendometriosiswererandomlydividedinto2groups:treatmentgroup(62patients)andcontrolgroup(58patients).PatientsinthetreatmentgroupweregivenintramuscularinjectionofDipherelineevery28daysforconsecutive3timesandorallytookwomen'sDan'eFukan

5、gJiangaofor6monthsatthesametime,whileinthecontrolgrouppatientswereinjectedwithDipherelinealoneevery28daysfor6times.Postoperativepainrelief,recurrencerate,pregnancyrate,medicationsideeffects,andtreatmentcostswerecomparedbetweenthe2groups.Results:Follow-upratewas98.3%（

6、118/120）.Painrelief(96.7%vs96.6%),recurrencerate(1.67%vs1.72%)andpregnancyrate(58.3%vs55.6%)werenotdifferbetweenthegroups（P>0.05）,whilethedrug'ssideeffectsandcostoftreatmentweredramaticallyfewerandlessinthetreatmentgroup（P<0.05）.Conclusion:Integratedmedicinetherapywi

7、thDan’eFukangJiangaoiseffectiveandsafewithlesspayasasupplementtoendometriosislaparoscopicsurgery.Keywordsendometriosislaparoscopicsurgerypost-operationdipherelinedan’efukangjiangao子宫内膜异位症(endometriosis,EMs)是育龄妇女的常见疾病,发病率为5％～15%。主要症状有慢性盆腔疼痛、痛经、性交痛、不规则下腹痛、月

8、经异常和不孕等,影响患者的生育和生活质量。目前，腹腔镜手术已成为子宫内膜异位症治疗的首选方法和诊治的金标准[1]。由于绝大多数患者为育龄妇女,所以只能采取保守性或半根治性手术,且术后极易复发,有报道经腹腔镜保守治疗术后1年内复发率19%[2]。为了减少术后复发,