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ID:36791878
大小:749.43 KB
页数:25页
时间:2019-05-15
《冠脉病变程度与脑钠肽的相关性研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、浙江大学硕士学位论文中文摘要冠脉病变程度与脑钠肽的相关性研究浙江大学医学院内科学(心血管病学)硕士研究生导师葛萱胡申江(教授)中文摘要目的:研究无心力衰竭的冠心病患者冠脉病变程度与血浆BNP水平的相关关系及其临床意义。方法:选取临床符合冠心病诊断且冠脉造影阳性的非心衰患者70例,分为三个组:稳定型心绞痛组24例,不稳定型心绞痛组25例,心肌梗死组21例,同时选取冠脉造影阴性者20例做对照组。用ELASA法测定血浆BNP浓度,并在冠状动脉造影后计算冠状动脉病变的支数和评分,比较冠心病各组与对照组的BNP水平,并对冠状动脉病变支数、评分与BNP水平作相关性分析。
2、结果:冠心病各组BNP水平均高于对照组,尤以心肌梗死组明显,与对照组之间存在显著性差异(P3、ofcoronaryarterylesionsandplasmabrainnatriureticpeptideCollegeofMedicine,ZhejiangUniversityCardiologyObjection,PostgraduateGeXuanSupervisorHuShenjiangAbstractToexploretherelationshipandtoinvestigatetheclinicalsignificancebetweentheextentofcoronaryarterylesionsandplasmabrainnatriure4、ticpeptide(BNP)levelsinthepatientsofcoronaryarterydisease(CAD)withoutcongestiveheartfailure.Methods:70CADpatientswithoutcongestivheartfailure,whichhadbeendiagnosedinclinicandundergonecoronaryarteriongraphy(CAG),weredividedinto3groups:24subjectswithstableangina(SA),25subjectswithuns5、tableangina(UA),21subjectswithmyocardialinfarction(MI).Atequalpace,20subjectswereenrolledasthecontrolgroup.PlasmaBNPconcentrationsweremeasuredwithELASA.Theextentofcoronaryarterylesionswereestimatedbytheconorarylesionvesselandscore.TheBNPlevelswerecomparedbetweenpatientsgroupswithco6、ntrolgroup,andanalysisedwiththeconorarylesionvesselandscore.IV浙江大学硕士学位论文英文摘要Results:TheBNPconcentrationsoftheCADgroupswereallhigherthanthoseofthecontrolgroup.TherewassignificantdifferenceinMIgroupcomparingtocontrolgroup(P7、elated(P8、edwiththeBNPlevel.Determin
3、ofcoronaryarterylesionsandplasmabrainnatriureticpeptideCollegeofMedicine,ZhejiangUniversityCardiologyObjection,PostgraduateGeXuanSupervisorHuShenjiangAbstractToexploretherelationshipandtoinvestigatetheclinicalsignificancebetweentheextentofcoronaryarterylesionsandplasmabrainnatriure
4、ticpeptide(BNP)levelsinthepatientsofcoronaryarterydisease(CAD)withoutcongestiveheartfailure.Methods:70CADpatientswithoutcongestivheartfailure,whichhadbeendiagnosedinclinicandundergonecoronaryarteriongraphy(CAG),weredividedinto3groups:24subjectswithstableangina(SA),25subjectswithuns
5、tableangina(UA),21subjectswithmyocardialinfarction(MI).Atequalpace,20subjectswereenrolledasthecontrolgroup.PlasmaBNPconcentrationsweremeasuredwithELASA.Theextentofcoronaryarterylesionswereestimatedbytheconorarylesionvesselandscore.TheBNPlevelswerecomparedbetweenpatientsgroupswithco
6、ntrolgroup,andanalysisedwiththeconorarylesionvesselandscore.IV浙江大学硕士学位论文英文摘要Results:TheBNPconcentrationsoftheCADgroupswereallhigherthanthoseofthecontrolgroup.TherewassignificantdifferenceinMIgroupcomparingtocontrolgroup(P7、elated(P8、edwiththeBNPlevel.Determin
7、elated(P8、edwiththeBNPlevel.Determin
8、edwiththeBNPlevel.Determin
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