欢迎来到天天文库
浏览记录
ID:36634304
大小:35.50 KB
页数:9页
时间:2019-05-13
《瑞芬太尼芬太尼及瑞芬太尼复合全麻的对照研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、瑞芬太尼芬太尼及瑞芬太尼复合全麻的对照研究作者:周清河肖旺频姚明安尔丹杜炎芳【摘要】目的对比研究瑞芬太尼、芬太尼复合瑞芬太尼在全麻术中应用的可行性和有效性。方法ASAⅠ~Ⅱ级腹部胃肠道手术患者60例随机分为三组:F、R组和RF组,每组20例。F组血浆靶控芬太尼术中镇痛,芬太尼血浆靶浓度根据手术刺激调整,手术结束前半小时停止;R组用瑞芬太尼替代芬太尼;RF组瑞芬太尼复合芬太尼,胃肠道吻合操作完成前主要由芬太尼维持镇痛,其后主要由瑞芬太尼维持镇痛。结果R组诱导时发生呛咳、肌肉强直、心动过缓均比其余两组多。R
2、组苏醒期MAP和HR与其余两组相比明显增高(P<0.05)。苏醒期R组发生躁动、高血压、心动过速均比其余两组增多明显。与F组相比,R和RF组拔管时间、出恢复室时间明显缩短(P<0.05)。RF组瑞芬太尼用量与R组相比明显减少(P<0.05),RF组芬太尼用量与F组相比明显减少(P<0.05)。R、RF组的拔管后即刻、离开PACU、拔管后1hOAA/S评分明显比F组高(P<0.05)。RF组患者拔管后即刻、离开PACU时疼痛评分与R组相比,差异显著(P<0.05)。结论
3、三种麻醉方法术中均能提供良好的镇痛,满足手术要求。但瑞芬太尼联合芬太尼既能提供完善的镇痛,维持术中血流动力学平稳,术毕又能苏醒迅速且苏醒质量高。9【关键词】芬太尼瑞芬太尼全身麻醉靶控输注 【Abstract】ObjectiveTomakeacomparativestudyonthefeasibilityandvalidityofusingremifentanil、fentanylandremifentanilingeneralanaesthesia.Methods60ASAclassⅠ~Ⅱpatien
4、tsundergoingabdomenoperationswererandomlydividedintothreegroups:groupF、groupRandgroupRFwith20casesineachgroup.IngroupF,analgesiawasinducedandmaintainedwithTCIfentanyl.Thetargetplasmaconcentrationoffentanylwasadjustedbasedonoperationstimulationandstoppeta
5、t30minbeforetheendofsurgery.InGroupR,fentanylwasreplacedbyremifentanil.InGroupRF,analgesiawasinducedandmaintainedwithTCIremifentanil-fentanyl,analgesiawasmaintainedwithfentanylbeforegastrointestinaltractanastomosisandwithremifentanilafterwards.ResultsThe
6、occurrenceofcough、muscletwitch、bradycardiaingroupRweremorethanothertwogroupsduringinducement.MAPandHRingroupRweresignificantlyhigherthanothertwogroupsduringrecoveryfromanesthesia(P<0.05).Theoccurrenceoffidget、hypertension、tachycardiaweremorethanothert
7、wogroupsduringrecoveryfromanesthesia(P<0.05).Thedurationfromterminationof9anesthesiatotracheaextubationandthestayinPACUwassignificantlyshorteringroupRandgroupRFthaningroupF(P<0.05).ThequantityofremifentanilusedingroupRFwassignificantlylowerthaningr
8、oupRandthequantityoffentanylusedingroupRFwassignificantlylowerthaningroupF(P<0.05).TheOAA/SscoresweresignificantlygreateringroupRandgroupRFthaningroupFatthetimepointoftracheaextubation、leavingPACUand1haftertracheaextuba
此文档下载收益归作者所有