资源描述:
《基于PARYLENE的柔性生物微电极阵列的研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、上海交通大学硕士学位论文基于Parylene的柔性生物微电极阵列的研究姓名:王亚军申请学位级别:硕士专业:微电子学与固体电子学指导教师:杨春生;刘景全20090201上海交通大学硕士学位论文摘要宽为50μm,间距为100μm。电极间间距为600μm,底部直径为60μm,高度大约为24μm,具有较好的半球形形貌。测试优化的电极在1kHz时,电极的阻抗和相位分别为54.12kΩ和-61.6°,阻抗中容抗占阻抗的主要部分。相比于传统的平面微电极阵列,在相同底面积上,半球形凸起能够增大电极的有效表面积,电极阻抗明显降低,同时凸起结构
2、保证电极刺激位点与神经细胞的良好接触,这有利于提高生物电刺激效果。关键词:MEMS,神经工程,ParyleneC,微电极阵列第II页上海交通大学硕士学位论文摘要ResearchofParylene-basedFlexibleMicroelectrodeArrayABSTRACTNeuroengineeringisaninterdisciplinewhichrelatestoneuroscience,microelectronictechnique,materialScience,informationscience,etc,
3、whichishelpfulforinvestigatingtheoperatingmechanismoftheneuralsystemandsolvingtheproblemsrelatedtoneuraldisordersandneuralrehabilitation.Themicroelectrodeistheinterfacebetweennervoussystemandcircuit,whichisthemostcriticalcomponentinneuroengineeringsystems.AMEMS-bas
4、edflexiblemicroelectrodearray(MEA)isstudiedinthisthesis,whichisfabricatedbyphotoresistthermalmeltingtechnology,chemicalvapordepositionParyleneC.Themaincontentsandconclusionarestatedasfollows:ThecouplingcapacitancebetweeninterconnectlinesareanalyzedbyAnsys,andthecur
5、rentdensityofdifferentsurfaceareaisanalyzedbyComsol.SomekeyquestionsforthefabricationofMEAarediscussed,accountingforelectrodepackagingmaterials,interconnectlinesandelectrodematerial,electrodegeometry.Basedontheanalyzingresult,theflexibleMEAisfabricated.Thekeyproces
6、sesduringthefabricatingMEAisresearched,includephotoresistmeltingandetchingParylenefilmsbyRIE.Theelectrochemicalimpedancespectroscopyofasingleelectrodeistestedin0.9%NaClsolution.Thetestingdataareanalyzed,andsomeadvicesareputforwardforfurtherimprovingtheelectrodeperf
7、ormances.Thefabricatedelectrodeis5×5grid,coveringanareaof3mm×3mm.第III页上海交通大学硕士学位论文摘要Thewidthoftheinterconnectlinesis50μmandthespaceis100μm.Thespaceoftwoelectrodesis600μm.Eachelectrodeis60μmdiameterandtheheightisabout24μm,whichhaveanapproximatelyhemisphericalsurface
8、profile.Theelectrodetypicallyexhibitanimpedanceof54.12kΩandthephaseshiftof-61.6°at1kHz,respectively,whichindicatesthatthemicroelectrodeismoredomi