mir-155在创面愈合中的作用及机制研究

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1、分类号UDC密级公开miR-155在创面愈合中的作用及机制研究杨龙龙培养类别全日制学位类型学术学位一级学科(专业类)临床医学二级学科(专业)外科学（烧伤）研究方向创面愈合指导教师胡大海教授（主任医师）培养单位西京医院烧伤与皮肤外科二O一五年五月第四军医大学博士学位论文目录缩略语表·················································································································1中文摘要····················

2、·····························································································3ABSTRACT············································································································6前言·································································

3、··············································10文献回顾···············································································································12正文···············································································································

4、27第一部分miR-155促进创面愈合及相关机制研究··············································27实验一miR-155通过增快角质形成细胞迁移加速创面上皮化而促进创面愈合···281材料············································································································282方法···············································

5、·····························································303结果············································································································354讨论···································································································

6、·········43实验二miR-155促进角质形成细胞迁移的机制研究··········································461材料············································································································462方法··················································································

7、··························483结果············································································································524讨论············································································································58实验三miR-155对创面局部炎症反应及愈后纤维

8、化的影响·······························611材料··············