自噬在布比卡因肌毒性中的作用及机制研究

《自噬在布比卡因肌毒性中的作用及机制研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、分类号：R685单位代码：10312密级：学号：20122119博士学位论文题目：自噬在布比卡因肌毒性中的作用及机制研究研究生：李荣荣指导教师：丁正年教授学科专业：麻醉学学院名称：南京医科大学第一临床医学院完成时间：二〇一五年六月南京医科大学学位论文原创牲声明本人郑重声明：所呈交的论文是本人在导师的指导下，独立进行研究工作矫取得的成果。除了文中特别加，！＾标法引用的内容外本论文不包含任何其他个人或集体已经发表或撰写的成果作品。对本文的研究做出重要贡献的个人和集体，均已在文中Ｗ明确方式标明。本人完全意识到本声明的法律后果由本人承担。６作者签名

2、：日期：年月７日■１５导师签名：了日期：＞年６好７日学位论文版权使用授极书本学位论文作者完全了解学校有关保留、使用学位论文的规定，同意学校保留并向国家有关部口或机构送交论文的复印件和电子版，允许论文被查阅和借陶。本人授权南京医科大学可将本学位论文的全部或部分内容编入有关数据库进行检索。，可Ｕｉ采用影印、缩印或扫描等复制手段保存和汇编本学位论文＂＂本学位论文属于（请在Ｗ下相应方框内打Ｖ）：１、，在。保密□＿＿年解密后适用本授权书２、不保密ｘ／。作者签名：日孤年６月７曰裏秦导师签名：日期：年６月曰ｙ＾目录中英文缩略词

3、········································································································1中文摘要················································································································3英文摘要·····························································

4、···················································12引言················································································································23参考文献················································································································27

5、正文第一部分布比卡因引起肌毒性和自噬体的增加················································30前言································································································30材料与方法····························································································31结果··············

6、··················································································41讨论································································································49参考文献································································································51第

7、二部分布比卡因引起自噬体增加的机制························································54前言································································································54材料与方法····························································································56结果··