阿伐他汀对心脏病人非心脏手术围手术期心血管事件发生率的影响

《阿伐他汀对心脏病人非心脏手术围手术期心血管事件发生率的影响》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089_学号或申请号13121HebeiMedicalUniversity硕士学位论文在职科学学位阿伐他汀对心脏病人非心脏手术围手术期心血管事件发生率的影响学位申请人：钦佩导师：马景涛副教授专业：内科学二级学院：第四医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则,

2、承担相应法律责任。研究生签名导师签章irfv^r二级学院领导盖章：U年y月0曰河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定•本论文由本人独立撰写,文责自负。研究生签名：导师签章：如^年：r月W日目录中文摘要·············································································1英文摘要·········································

3、····································2研究论文阿托伐他汀对心脏病人非心脏手术围手术期心血管事件发生率的影响前言·············································································4材料与方法····································································5结果·······································································

4、······6附表·············································································9讨论·············································································12结论·············································································15参考文献·············································

5、··························15综述阿托伐他汀对心脏病人非心脏手术围手术期心血管事件发生率影响的研究进展·····························································20致谢···················································································29个人简历·············································································30中

6、文摘要阿托伐他汀对心脏病人非心脏手术围手术期心血管事件发生率的影响摘要目的：本研究通过观察术前应用阿托伐他汀对冠心病患者非心脏手术围手术期心血管死亡率的影响，旨在指导心脏病患者非心脏手术围手术期用药。方法：选择2013-12～2014-12在河北省四院的非心脏手术的心脏病患者，入选200例。其中试验组96例，对照组104例。采用随机数字表随机分为两个组，试验组与对照组。排除标准：口服药物困难患者；活动性肝病或原因不明的转氨酶持续升高患者；近期新发生脑出血患者；高危手术患者；对阿托伐他汀过敏者；术中出现其他由于手术本身意外导致心脏并发症。在常规治疗基础上，术前7天开始给予口服阿托伐他汀（辉瑞

7、制药有限公司，商品名：立普妥，国药准字H20051407）20mg/次,每日1次。对照组不给药。为了使患者依从性更好，入选患者出院后进行电话随访。由专人负责，对心脏病人非心脏手术围手术期血压、脉搏、心电监护、中心静脉压监测，观察心电图ST-T变化，随访术后心血管事件发生率（监测血压、心电图、心脏彩超变化）以及围术期心梗、心绞痛、房颤、室早、肾衰竭、血脂、心性死亡率，由专人记录。所有患者资料均用光盘保存，用于前后对比。结果