铅在大脑内的分布及其对树突棘可塑性影响的初步研究

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1、分类号R135.1+1第四军医大学UDC613.6TheFourthMilitaryMedicalUniversity密级公开硕士学位论文铅在大脑内的分布及其对树突棘可塑性影响的初步研究赵再华培养类别全日制学位类型学术学位一级学科(专业类)公共卫生与预防医学二级学科(专业)劳动卫生与环境卫生学研究方向环境毒理学指导教师陈景元教授培养单位军队劳动与环境卫生学教研室二O一五年五月第四军医大学硕士学位论文目录缩略语表····················································

2、··········································1中文摘要······························································································3英文摘要······························································································7前言················

3、·············································································11文献回顾·····························································································13正文···············································································

4、··············26第一部分铅在大鼠大脑内的分布···························································261材料···························································································262方法·····································································

5、······················273结果···························································································304讨论···························································································35第二部分铅暴露对大鼠海马神经元树突棘可塑性的影响···················

6、··········371材料···························································································372方法···························································································393结果····················································

7、·······································424讨论···························································································45第三部分Neuroligin-1在铅暴露损伤树突棘可塑性中作用的初步探讨·············481材料····································································

8、·······················482方法···························································································513结果·······························································