经直肠与经会阴途径前列腺穿刺活检的对比研究

《经直肠与经会阴途径前列腺穿刺活检的对比研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、分类号：R692学校代码：10392学科专业代码：105109学号：2151003525硕士学位论文经直肠与经会阴途径前列腺穿刺活检的对比研究Comparisonofprostaticbiopsies:transrectalapproachandtransperinealapproach学位类型：临床医学硕士所在学院：省立临床医学院申请人姓名：王晓宏学科、专业：外科学（泌尿外）导师：叶烈夫教授研究起止日期：2017年12月至2018年4月答辩委员会主席：何延瑜教授答辩日期：2018年05月29日二○一八年五月福建医科大学硕士学位论文福建医科大学硕士学位论文目录中英文缩略词对照表

2、„„„„„„„„„„„„„„„„„„1中文摘要„„„„„„„„„„„„„„„„„„„„„„„2英文摘要„„„„„„„„„„„„„„„„„„„„„„„3引言„„„„„„„„„„„„„„„„„„„„„„„„„41资料与方法„„„„„„„„„„„„„„„„„„„„„51.1一般基本临床资料„„„„„„„„„„„„„„„„51.2方法„„„„„„„„„„„„„„„„„„„„„61.2.1穿刺仪器准备„„„„„„„„„„„„„„„61.2.2穿刺前准备„„„„„„„„„„„„„„„„61.2.3穿刺操作„„„„„„„„„„„„„„„„„71.2.4术后处理„„„„„„„„„„„„„„„„

3、„91.2.5统计学处理„„„„„„„„„„„„„„„102结果„„„„„„„„„„„„„„„„„„„„„„„„102.1肿瘤检出率及穿刺后并发症比较„„„„„„„„„102.2穿刺后并发症预后及转归„„„„„„„„„„„„113讨论„„„„„„„„„„„„„„„„„„„„„„„„124结论„„„„„„„„„„„„„„„„„„„„„„„„17参考文献„„„„„„„„„„„„„„„„„„„„„„„17综述„„„„„„„„„„„„„„„„„„„„„„„„„22致谢„„„„„„„„„„„„„„„„„„„„„„„„„29福建医科大学硕士学位论文中英文缩略词对照表缩略词英文全称中文全称T

4、RTransrectalprostatebiopsy经直肠途径前列腺穿刺活检TPTransperinealprostatebiopsy经会阴途径前列腺穿刺活检SIRSSystemicInflammatoryResponseSyndrome全身炎症反应综合症PCaprostatecancer前列腺癌PSAProstatespecificantigen前列腺特异性抗原TRUSTransrectalultrasonography经直肠超声PVProstatevolume前列腺体积MODSmultipleorgandysfunctionsyndrome多器官功能障碍综合征福建医科大学硕

5、士学位论文经直肠与经会阴途径前列腺穿刺活检的对比研究摘要目的：比较经直肠与经会阴途径前列腺穿刺活检诊断前列腺癌的应用价值及安全性。方法：回顾性分析福建省立医院2014年3月-2017年12月271例疑为前列腺癌行经直肠或经会阴途径前列腺穿刺活检患者的临床资料，收集两组患者的前列腺癌检出率及穿刺后并发症等相关资料并作分析。结果：经直肠与经会阴途径穿刺组前列腺癌总体检出率分别为35.86%、37.30%，PSA位于不同的区间（PSA＜10ng/ml、10ng/ml≤PSA≤20ng/ml、PSA＞20ng/ml）时经直肠与经会阴途径穿刺组前列腺癌检出率分别为13.04%、14.58

6、%，20.75%、29.72%，76.08%、70.73%，前列腺体积位于不同的区间（20ml≤V＜25ml、25ml≤V＜50ml、50ml≤V＜75ml、V≥75ml）时经直肠与经会阴途径穿刺组前列腺癌检出率分别69.23%、66.66%，41.17%、44.18%，21.05%、26.82%，21.73%、32.25%，差异均无统计学意义（P＞0.05）。经直肠与经会阴途径穿刺组术后并发症总体发生率分别为44.13%、3.17%,经直肠穿刺组患者穿刺后感染、血尿、血便、尿潴留发生率分别为14.48%、18.62%、4.82%、4.82%，均明显高于经会阴组0.79%、2.

7、38%、0%、0%的发生率，存在显著统计学差异（P<0.05）。经直肠穿刺组需药物控制的疼痛、一过性晕厥发生率均为0.68%，而经会阴组则为0，两组无明显差异（P＞0.05）。根据Clavien—Dindo并发症分级系统，经直肠与经会阴途径穿刺组I级、II级并发症分别为28.96%、2.38%，12.41%、0.79%，均存在明显差异（P＜0.05），经直肠与经会阴途径穿刺组III级、IV级、V级并发症分别为0.68%、0,2.06%、0，0、0，均无明显差异（P＞0.05）。结论：经会阴前