Beclin-1基因沉默对前列腺增生上皮细胞BPH-1自噬及凋亡作用机制的研究

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1、分类号：R694学校代码：10392学科专业代码：100210学号：2151003045密级：（注明密级与保密期限）硕士学位论文Beclin-1基因沉默对前列腺增生上皮细胞BPH-1自噬及凋亡作用机制的研究ThestudyofBeclin-1genesilencingontheautophagyandapoptosisoftheProstatichyperplasiaepithelialcells学位类型：医学硕士所在学院：临床医学部申请人姓名：张松学科、专业：外科学（泌尿外科学）导师：刘荣福教授研究起止日期：2017年3月至

2、2018年1月答辩委员会主席：薛学义教授答辩日期：2018年5月15日二○一八年五月福建医科大学硕士学位论文福建医科大学硕士学位论文目录中文摘要····································································································································1英文摘要·························································

3、···········································································3第一章前言··························································································································51.雄激素与良性前列腺增生·················································

4、······························52.细胞自噬与Beclin-1基因·············································································63.BPH与细胞凋亡关系···························································································74.细胞自噬与凋亡间的互相关联·····················

5、················································85.Beclin-1基因与PI3K-AKT-mTOR信号通路关系······························96.实验内容及研究意义························································································106.1实验内容··············································

6、··························································106.2研究意义········································································································11第二章材料和方法·····················································································

7、···················121.主要材料及试剂···································································································122.主要实验仪器········································································································133.主要试剂配制·············

8、···························································································144.实验方法·······································