不同年龄女性冠心病患者冠状动脉病变特点及危险因素研究

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1、授予单位代码10089学号或申请号13126#vni.HebeiMedicalUniversity硕士学位论文在职科学学位不同年龄女性冠心病患者冠状动脉病变特点及危险因素研究学位申请人：尹航导师：刘凡教授专业：内科学二级学院：第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所

2、有。否则，承担相应法律责任。/f笑Jf、.NrA'J.‘‘/.,,.d研究生签名导师签章二级学院镇导盖章：t年.贞zB河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人己经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。目录中文摘要·············································································1英文摘要·································

3、············································2研究论文不同年龄女性冠心病患者冠状动脉病变特点及危险因素研究前言·············································································3材料与方法····································································4结果·····························································

4、················7附表·············································································9讨论·············································································12结论·············································································17参考文献·····························

5、··········································17综述女性冠心病危险因素及防治进展······································20致谢···················································································35个人简历·············································································36中文摘要不同年龄女性冠心病患者冠状动脉病变特

6、点及危险因素研究摘要目的：探讨不同年龄女性冠心病患者冠状动脉病变特点及危险因素。方法：选择448例女性冠心病患者，根据患者年龄分为≤40岁组、41～50岁组、51～60岁组、＞60岁组。比较四个不同年龄组的一般情况、冠脉造影结果及危险因素。结果：各年龄组女性冠心病患者在体重指数、吸烟指数、冠心病家族史方面无明显差别，随着年龄增长，高血压和糖尿病发病比例明显增加。≤40岁组在高血脂、肾功能不全、高尿酸血症方面明显低于其它各组，且随着年龄增长，各项危险因素及程度有增加趋势。不同年龄女性冠心病患者，随着年龄增长单支病变患者比例降低，而多支病变患者比例增大。不同年龄女性冠心病患者，随着

7、年龄增长，闭塞病变发病率明显增加，76%～99%狭窄发病率明显增加，50%～75%狭窄发病率降低。不同年龄女性冠心病患者，随着年龄增长，B型病变和C型病变发病率明显增加。结论：对传统的危险因素进行综合干预，还需针对女性特有的危险因素进行干预方可更有效的降低女性冠心病的发生风险，改善其预后。关键词：冠心病,冠状动脉,危险因素,冠状动脉造影,患者1英文摘要Researchofriskfactorsandpathologicalcharacteristicsofdifferentagefemale