3t磁共振动态增强扫描及弥散加权成像在鉴别乳腺良恶性病变应用研究

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1、硕士学位论文Studyof3Tdynamiccontrast--enhancedanddiffusion-weightedMRimagingindifferentialdiagnosisbetweenbenignandmalignantbreastlesionsobjectiveName：WuHui—YingSupervisor：Prof．ChenYan—PingABSTRACT1．ToinvestigatethefeasibilityofbreastMRlwithbodysurfacecoilandself-madebreaststen

2、tinhi．gh-magneticfield(3．or)MRscanner．2．Toevaluatethevalueofdynamiccontrast-enhancedMRImaging(DCE—MRI)indifferentialdiagnosisbetweenbenignandmalignantbreastlesionsbyusingLiverAcquisitionwithVolumeAcceleration(LAVA)techniqueandanalyzingthemorphologicfeaturesandhemodynamicc

3、haracteristicsofbenignandmalignantbreastlesions．3．Toexplorethevalueofquantitativeapparentdiffusioncoefficient(ADC)indifferentialdiagnosisbetweenbenignandmalignantbreastlesionsbyusingdiffusion-weightedMRImaging(DWI)withASSCTtechniqueatdifferentbvalues．PartIStudyofLAVAdynaI

4、Iliccontrast-enhancedMRImagingindifferentialdiagnosisbetweenbenignandmalignantbreastlesionsMaterialsandMethods1．Subjects42(totally47lesions，10casesof1malignantlesions，32casesof36benignABSTRACTlesions)patientswithbreastlesionswereenrolledduringJuly2007toFebruary2008inNanfa

5、ngHospital．Allthesubjectswereconfirmedbypathology．2．Equipmentandcontrastmedium①AllthepatientswereperformedwithGESignaEXCITEHD3．0Tsuperconductingmagneticresonancescanner．(墓)Abdomensurface8-channelphasedarraycoilandself-madebreaststentwereused．③Gd—DTPAWasinjectedasparamagne

6、ticcontrastmediumwithhighpressureinjection(Ulrichcorp)．@DCE．MRIdatawaspost-processedusingFunctoolSER(signaenhanceratio)so,warepackageonAW4．3workstation．3．Examinationtechnique3．1PlainscanningBilateralbreastaxialTlWI，axialandsagittalFSET2W1withfatsuppressionWereperformedwit

7、hscanparametersasfollowings：axialTlWI+FS(TR／TE=450／9．7ms)andaxialT2WI+FS(TR／TE=4000／85ms)with6mmslicethickness，lmmgap，FOV=32cmx32cm，NEX=2．0，320x224matrix；SagittalFSET2WI+FS(4675／85ms)with5mmslicethickness，lmmgap，FOV=22cmx22cm，NEX=2．0，320×224matrix．3．2LAVADCE．MRIDynamiccon

8、trast-enhancedMRIWasperformedwithLAVAsequence(TR／TE=3．6／1．7ms，200flipangle，4．4mmslicethicknesswi