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时间:2019-03-06
《玉米须总皂苷对病因性糖尿病模型小鼠的降糖效应》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、万方数据中国临床康复第7D卷第39期2006~10—20出版ChineseJournalofClinicalRehabilitation,October202006V01.10No.39玉米须总皂苷对病因性糖尿病模型小鼠的降糖效应苗明三1,苗艳艳2,宰炎冰2,史晶晶2木木☆123·基础研究·1河南中医学院,2河南中医学院药理室,河南省郑州市450008苗明三☆,男,1965年生,河南省郑州市人,汉族,2003年北京中医药大学毕业,博士,教授,主要从事中药药理教学方面的研究。教育部新世纪优秀人才支持计划(NCET—04—0657)+;河南省高等学校创新人才培养工程(2004—23P中图
2、分类号:R587.1文献标识码:A文章编号:1671—5926(2006)39—0123~03收稿日期:2006-06—24修回日期:2006一07—17(06—50—6-4692/ZS·I助EffectofsaponinextractedfromZeamaysLondecreasingthebloodglucoselevelofmicemodelsofaetiologicaldiabetesMiaoMing—sanl.MiaoYan—yon2.ZaiYan—bin92,ShiJing—rin921HenanCollegeof7rraditionalChineseMedicine.Z
3、hengzhou450008.HenanProvince,China;2DepartmentofPharmacology,HenanCollegeofTraditionalChineseMedicine.Zhengzhou450008,HenanProvince.ChinaMiaoMing—san-A-,Doctor.Professor,HenanCollegeofTraditionalChineseMedicine,Zhengzhou450008,HenanProvince,China’Supportedby:ProgramforNewCenturyExcellentTalents
4、inUniversities.MinistryofEducation.No.NCET一04—0657*;theInnovationTalentsProjectinAdvancedSchoolsofHenanProvince.No.2004—23+Received:2006一06-24Accepted:2006_07-17AbstractAn疽:ToobservetheeffectofsaponinextractedfromZeamaysLfZMLS)on血eaetiologicaldiabeticmodelmiceinducedbyiniectionofstreptozotocina
5、ndirrigationofsucrosewater,andexploretheroleofZMLSindecreasingthelevelofbloodglucose.M【ETHoDS:TheexperimentwasconductedatanimalexperimentcenteroftheHenanCollegeofTraditionalChineseMedicinefromFebruarytoJune2002.①Totally60cleangradeKunmingmicewereselcotedandrandomlydividedinto6groups:blankcontro
6、lgroup,modelgroup,metformingroup,large,middle,small—doseofZMLSgroupswith10animalsineverygroup.TheZMLSwasprovidedbytheChemicalLaboratoryofHenanCollegeofTraditionalChineseMed而ne.②Excepttheblankcontrolgroup,theotherfivegroupswerei.jectedwiththesmalldoseStreptozotocinandirrigatedwithsucrosewatertoe
7、stablishthediabetiemodel,afterwhichthemiceofthelarge,middle,small.doseofZMLSgroupsweregiven400,200and100mg/kgZMLS(concentrationof20,10,5g/L,thefeedingvolumewas0.2mL/10g),respectively;themetformingroupwasinfusedwith0:5g/ksmetformin
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