当归多糖对2型糖尿病预防及治疗作用的初步研究

当归多糖对2型糖尿病预防及治疗作用的初步研究

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时间:2019-03-05

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1、分类号学号M201175295学校代码10487密级硕士学位论文当归多糖对2型糖尿病预防及治疗作用的初步研究学位申请人杨秋香:学科专业:中药学硕士指导教师:王凯平教授答辩日期:2013年5月ADissertationSubmittedinPartialFulfillmentoftheRequirementsfortheDegreeofMasterofMedicinePreliminaryResearchonthePreventionandTreatmentofTypeIIDiabetesofAng

2、elicaSinensisPolysaccharideinMiceCandidate:YangQiuxiangMajor:MasterofChineseMateriaMedicaSupervisor:Prof.WangKaipingHuazhongUniversityofScienceandTechnologyWuhan,Hubei430074,P.R.ChinaMay,2013独创性声明本人郑重声明,本学位论文是本人在导师指导下进行的研究工作及取得的研究成果的总结。尽我所知,除文中已经标明引用的

3、内容外,本论文不包含任何其他个人或集体已经发表或撰写过的研究成果。对本文的研究做出贡献的个人和集体,均已在文中以明确方式标明。本人完全意识到本人将承担本声明引起的一切法律后果。学位论文作者签名:日期:年月日学位论文版权使用授权书本学位论文作者完全了解学校有关保留、使用学位论文的规定,即:学校有权保留并向国家有关部门或机构送交论文的复印件和电子版,允许论文被查阅和借阅。本人授权华中科技大学可以将本学位论文的全部或部分内容编入有关数据库进行检索,可以采用影印、缩印或扫描等复制手段保存和汇编本学位论文。

4、保密□,在_____年解密后适用本授权书。本论文属于不保密□。(请在以上方框内打―√‖)学位论文作者签名:指导教师签名:日期:年月日日期:年月日目录摘要··································································································1ABSTRACT····································································

5、·······················4前言··································································································7第一部分当归多糖的提取与纯化·······························································111.当归粗多糖的提取·····································

6、········································112.当归粗多糖的纯化············································································133.当归多糖纯度和分子量的鉴定·····························································154.讨论与结论····································

7、·················································19第二部分当归多糖对前趋糖尿病小鼠的预防作用研究···································211.HFD诱导前趋糖尿病小鼠模型的建立····················································212.当归多糖对前趋糖尿病小鼠预防作用的药效学研究···································243.当归多糖

8、对前趋糖尿病小鼠预防作用的组织形态学观察·····························324.讨论与结论·····················································································38第三部分当归多糖对2型糖尿病小鼠的治疗作用研究···································401.HFD+STZ诱导2型糖尿病小鼠模型的建立···············

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