二苯乙烯苷抗痴呆作用及机制研究

二苯乙烯苷抗痴呆作用及机制研究

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页数:71页

时间:2019-03-04

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1、学校代码:10600学号:101076学位类型:科学学位广西中医药大学硕士学位论文二苯乙烯苷抗痴呆作用及机制研究研究生:刘玲导师:黄忠仕教授院系(部所):药学院专业:药理学研究方向:抗痴呆药理研究完成日期:2013年5月20日目录中英文缩略词汇表·····································································1中文摘要··················································································2英文摘要

2、··················································································4引言··················································································6正文··················································································9第一部分二苯乙烯苷对SAMP8小鼠学习记忆能力的改善作用···

3、·······91实验材料和方法·····································································92实验结果·············································································103讨论···················································································15第二部分二苯乙烯苷对SAMP8小鼠APP、PS1、P

4、S2及ApoEmRNA表达的影响················································································181实验材料和方法···································································182实验结果·············································································213讨论······················

5、·····························································31第三部分二苯乙烯苷对SAMP8小鼠BACEmRNA表达的影响·······331实验材料和方法···································································332实验结果·············································································363讨论··················

6、·································································37第四部分二苯乙烯苷对SAMP8小鼠P-tau396蛋白表达的影响········391实验材料和方法···································································392实验结果·············································································413讨论···········

7、········································································43结论················································································44结语与展望·············································································45参考文献······································

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