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1、UseR!SeriesEditors:RobertGentlemanKurtHornikGiovanniG.ParmigianiForfurthervolumes:www.springer.com/series/6991SørenHøjsgaardDavidEdwardsSteffenLauritzenGraphicalModelswithRSørenHøjsgaardSteffenLauritzenDepartmentofMathematicalSciencesDepartmentofStatisticsAalborgUniversityUniversityofOxfordAal
2、borgOxfordDenmarkUKDavidEdwardsCentreforQuantitativeGeneticsandGenomicsDepartmentofMolecularBiologyandGeneticsAarhusUniversityAarhusDenmarkSeriesEditors:RobertGentlemanKurtHornikPrograminComputationalBiologyDepartmentofStatistikandMathematikDivisionofPublicHealthSciencesWirtschaftsuniversitätWie
3、nFredHutchinsonCancerResearchCenterWienSeattle,WAAustriaUSAGiovanniG.ParmigianiTheSidneyKimmelComprehensiveCancerCenteratJohnsHopkinsUniversityBaltimore,MDUSAISBN978-1-4614-2298-3e-ISBN978-1-4614-2299-0DOI10.1007/978-1-4614-2299-0SpringerNewYorkDordrechtHeidelbergLondonLibraryofCongressControlNu
4、mber:2012931941©SpringerScience+BusinessMedia,LLC2012Allrightsreserved.Thisworkmaynotbetranslatedorcopiedinwholeorinpartwithoutthewrittenpermissionofthepublisher(SpringerScience+BusinessMedia,LLC,233SpringStreet,NewYork,NY10013,USA),exceptforbriefexcerptsinconnectionwithreviewsorscholarlyanalysi
5、s.Useinconnectionwithanyformofinformationstorageandretrieval,electronicadaptation,computersoftware,orbysimilarordissimilarmethodologynowknownorhereafterdevelopedisforbidden.Theuseinthispublicationoftradenames,trademarks,servicemarks,andsimilarterms,eveniftheyarenotidentifiedassuch,isnottobetakena
6、sanexpressionofopinionastowhetherornottheyaresubjecttoproprietaryrights.Printedonacid-freepaperSpringerispartofSpringerScience+BusinessMedia(www.springer.com)PrefaceGraphicalmodelsintheirmodernformhavebeenaroundsincethelate1970sandappeartodayinmanyareasofthesciences.Alongwiththeongoingdevelopmen
7、tsofgraphicalmodels,anumberofdifferentgraphicalmodellingsoftwareprogramshavebeenwrittenovertheyears.Inrecentyearsmanyofthesesoftwaredevelop-mentshavetakenplacewithintheRcommunity,eitherintheformofprovidinganRinterfacetoexist