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1、SpringerThesesRecognizingOutstandingPh.D.ResearchForfurthervolumes:http://www.springer.com/series/8790AimsandScopeTheseriesSpringerThesesbringstogetheraselectionoftheverybestPh.D.thesesfromaroundtheworldandacrossthephysicalsciences.Nominatedandendorsedbytworec
2、ognizedspecialists,eachpublishedvolumehasbeenselectedforitsscientificexcellenceandthehighimpactofitscontentsforthepertinentfieldofresearch.Forgreateraccessibilitytonon-specialists,thepublishedversionsincludeanextendedintroduction,aswellasaforewordbythestudentssu
3、pervisorexplainingthespecialrelevanceoftheworkforthefield.Asawhole,theserieswillprovideavaluableresourcebothfornewcomerstotheresearchfieldsdescribed,andforotherscientistsseekingdetailedbackgroundinformationonspecialquestions.Finally,itprovidesanaccrediteddocumen
4、tationofthevaluablecontributionsmadebytodaysyoungergenerationofscientists.Thesesareacceptedintotheseriesbyinvitednominationonlyandmustfulfillallofthefollowingcriteria•TheymustbewritteningoodEnglish.•ThetopicshouldfallwithintheconfinesofChemistry,Physicsandrelate
5、dinterdisciplinaryfieldssuchasMaterials,Nanoscience,ChemicalEngineering,ComplexSystemsandBiophysics.•Theworkreportedinthethesismustrepresentasignificantscientificadvance.•Ifthethesisincludespreviouslypublishedmaterial,permissiontoreproducethismustbegainedfromther
6、espectivecopyrightholder.•Theymusthavebeenexaminedandpassedduringthe12monthspriortonomination.•Eachthesisshouldincludeaforewordbythesupervisoroutliningthesignifi-canceofitscontent.•Thethesesshouldhaveaclearlydefinedstructureincludinganintroductionaccessibletosci
7、entistsnotexpertinthatparticularfield.XinZhangMultistateGTPaseControlCo-translationalProteinTargetingDoctoralThesisforChemistryacceptedbyCaliforniaInstituteofTechnology,Pasadena,CA,USA123AuthorSupervisorDr.XinZhangShu-ouShanTheScrippsResearchInstituteAssistantP
8、rofessorNorthTorreyPinesRd10550DivisionofChemistryandChemicalMailStop:BCC265,LaJollaEngineeringCA92037CaliforniaInstituteofTechnologyUSAPasadena,CA91125USAe-mail:xinzhang@scripps.e