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1、201R1eportMEDICINESINDEVELOPMENTFORHeartDiseaseandStrokePRESENTEDBYAMERICA’SBIOPHARMACEUTICALRESEARCHCOMPANIESBiopharmaceuticalResearchCompaniesAreDevelopingNearly300MedicinesforCardiovascularDiseaseiopharmaceuticalresearchcompaniesareMEDICINESINDEVELOPMENTF
2、ORHEARTDISEASEANDSTROKE*developing299newmedicinesfortwooftheBleadingcausesofdeathofAmericans—heartdiseaseAcuteCoronarySyndrome22AdjunctiveTherapies5andstroke.TheworkcontinuesthemomentumofdrugArrhythmia/AtrialFibrillation15discoverythathashelpedcutdeathsfromt
3、hesediseasesAtherosclerosis15by28percentbetween1997and2007.AllofthemedicinesCoronaryArteryDisease9areeitherinclinicaltrialsorawaitingreviewbytheHeartAttack17FoodandDrugAdministration.HeartFailure36Hypertension27AccordingtotheNationalCenterforHealthStatistics
4、,ImagingAgents11heartdiseasehastoppedthelistofkillerdiseaseseveryIschemicDisorders23LipidDisorders43yearbutonesince1900.(Theexceptionwas1918,PeripheralVascularDisease20whenaninfluenzaepidemickilledmorethan450,000PulmonaryVascularDisease17Americans.)Stroke27T
5、hrombosis28Thanksinlargeparttonewdrugtreatments,deathratesOther35fromheartdiseaseandstrokearefalling.In2008,strokedroppedtothefourthleadingcauseofdeathafterbeing*Somemedicinesarelistedinmorethanonecategory.thethirdforover50years.AccordingtotheNationalThemedi
6、cinesindevelopmentinclude43forlipidHeart,LungandBloodInstitute(NHLBI),ifdeathratesdisorders,suchashighcholesterol,36forheartfailure,werethesameasthoseof30yearsago,815,000more27forhighbloodpressure,17forheartattacks,andAmericanswoulddieofheartdiseaseannuallya
7、nd27forstroke.Manyofthepotentialmedicinesuse250,000morewoulddieofstroke.Thisreductionincutting-edgetechnologiesandnewscientificapproaches.deathratesis“oneofthegreattriumphsofmedicineForexample:inthepast50years,”accordingtocardiologistDr.EugeneBraunwaldofBrig
8、hamandWomen’sHospital•HumanstemcellsthatrestorecardiacfunctionbyinBoston.formingnewheartmuscle.•AnewanticoagulantthatregulatesclotformationtoMuchoftheprogressisduetothedevelopmentofpreventdeepve
