颈、股动脉内中膜厚度与血管内皮舒张功能与冠心病相关性分析

《颈、股动脉内中膜厚度与血管内皮舒张功能与冠心病相关性分析》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、硕士学位论文3．颈动脉、股动脉IMT及肱动脉FMD相关关系105例受试者颈动脉、股动脉IMT与肱动脉FMD之间呈明显负相关(相应产．0．69、，=．0．74，均P<0．001)a结论1．外周大动脉如颈动脉、股动脉，其位置表浅，易于辨认和寻找，高频超声能准确测量颈动脉、股动脉IMT，再因它价格低廉、无创、重复性好，可作为检测外周大动脉粥样硬化的一种较好检查方法；2．随着冠状动脉病变程度加重，颈动脉、股动脉IMT值增加，肱动脉FMD降低；3．颈动脉、股动脉IMT以及肱动脉FMD与冠状动脉粥样硬化密切相关，外周动脉粥样

2、硬化程度可间接反映冠状动脉病变的程度；4．冠心病患者存在颈动脉、股动脉IMT的显著增厚和肱动脉内皮依赖性舒张功能的显著受损，颈动脉、股动脉IMT与肱动脉FMD呈明显负相关，外周血管超声检测可作为观察动脉粥样硬化的工具，对冠心病有一定的辅助诊断作用，值得临床进一步推广应用。关键词：冠心病颈动脉股动脉内皮功能超声V硕士学位论文Relationshipsbeeencarotid，femoralarteryintima——mediathicknessandendothelialdilatedfunctioninpatie

3、ntswithBackgroundcoronaryarterydiseaseName：ZHANGQiongSupervisor：Prof．CHENAihuaABSTRACTCoronaryarterydisease(CAD)iscommondiseaseanditsincidencehasbeenincreasingyearbyyearinourcountry．Nowithasbecomeaseriousthreattohumanhealth，SOit'sveryimportanttodetectearlyath

4、erosclerosisandtakeactivepreventionandtreatment．Thoughcoronaryangiography(CAG)hasbeenthe”goldstandard”todiagnosethecoronaryheartdisease，itcostsalotandisinvasiveandneedadvancedequipmentsthatlimiteditsapplication，itcan’tbewidelyappliedandit'shardtomonitorpatien

5、t’Sconditionandprognosis．Now，itisanewtopictofindaneconomicalandsimplemethodtoasSeSScoronaryheartdiseaseinthehistoryofpreventionandtreatmentofcoronaryheartdisease．ThemaincauseofCADiscoronaryatherosclerosis．Asthecoronaryarteryandperipheralarteryareinthesamevasc

6、ularbeds，theatherosclerosisofthemisaffectedbythesameriskfactors，pathogenesisandpathophysiologyprocesses．AtherosclerosisisadiffuseprocessthatstartsearlyinchildhoodtoprogressiABSTRACTsymptomaticallyanditspathologicalprocesscRnbedividedintothreestages：vascularen

7、dothelialdysfunction，vascularintimalthickeningandtheformationofatheroscleroticplaque，vascularendothelialdysfunctionandintimalthickeningaretheearlystagesofatherosclerosis，thenthethickeningvascularintimalcanprogresstobeatheroscleroticplaque，that’Stheadvancedsta

8、ge．Intima—mediathickness(IMT)isthethicknessofintimalandmediaarterialwall，itisinvolvedintheinitiationofatherosclerosisandconsideredtobeanearlysignofatherosclerosis．In1986，Pignolietalfirstd