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ID:33666326
大小:5.11 MB
页数:74页
时间:2019-02-28
《微流控芯片的制备及电渗性能研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、摘要微流控芯片具有集成化程度高、效率高、消耗少等诸多优点,有着巨大的应用价值和潜力。但高昂的制造成本制约了芯片大规模的商业化应用。从制备材料、制备工艺及使用性能来看,玻璃的制备工艺成熟,应用性能优良,但制备工艺复杂,成本高;聚合物制备工艺简单,成本低,但应用性能差。本研究以廉价的载玻片和PDMS为材料,通过空气等离子体改性实现芯片的不可逆封接,制备了玻璃.PDMS、PDMS.PDMS芯片,并对芯片的电特性进行了研究。本文讨论了各工序对刻蚀玻璃沟道的影响,通过工艺参数的优化,制备出质量良好的沟道。利用光
2、刻和蚀刻技术,制备了硅和RFJ220负型光刻胶阳模。在阳模上浇注液态的PDMS单体,通过加热固化制得了含微通道的PDMS基片。利用空气等离子体在低温条件下对PDMS表面进行改性,提高了其表面的亲水性能,实现了芯片的不可逆封接。利用电流监测法对芯片的电渗性能进行了研究,重点分析了缓冲液种类、浓度、分离电压、表面活性齐iJ(SDS)、温度等对电渗流的影响,获得了稳定电渗性能的基本条件,为微流控系统的设计、测试、优化、应用提供了依据。关键词:微流控芯片;聚二甲基硅氧烷;光刻与刻蚀;电渗流ABSTRACTTh
3、emicrofluidicchiphasmanyadvantages,suchashighefficiency,highintegration,lowconsumptionandSOon,whichleadstohugepotentialandvaluableapplication.Butthehighpreparationcostlimitsitscommercialapplicationonalargescale.Theglassmicrofluidicchiphasagoodapplicatio
4、nperformance,butitrequiresacomplexfabricationprocessandthecostoffabricationistoohigh;thepolymermicrofluidicchiphasaneasyfabricationprocess,butithasapoorpropertyonthetest.Theglass-PDMS,PDMS-PDMSchipswithlow—costglassandPDMSasmaterialsarepreparedinthispap
5、er.Thesubstrateswhicharetreatedbyairplasmacansticktootherchipsfirmly.Andtheelectricalpropertiesofthechipsareinvestigated.Theeffectsofworkingproceduresonqualitiesofglasschannelsarediscussedinthispaper.Throughoptimizingtheparametersoftechnics,theglasschan
6、nelswithgoodqualitiesaregained.Usingphotolithograpandetchingtechniques,thepatternsusedtomouldPDMSarepreparedwithsiliconandRFJ一220photoresistasmaterials.ThePDMSchipswithmicrochannelaremadebyheatingtosolidifyafterpouringthePDMSfuidontothemicromachinedsili
7、conandphotoresistmaster.TheairplasmageneratedbymicrowaveischosentotreatPDMS.Theelectroosmosispropertiesofmicrofluidicchipsareanalyzedbythemethodofcurrentmonitoring.Theeffectsincludingbuffersolution’Scategoryandconcentration,separationvoltage,surfactant(
8、SDS),temperatureontheelectroosmosisarestudied.Thebasicconditionssteadyingtheelectroosmosisisobtained,whichprovidesfoundationfordesign,testing,optimizing,applicationofmicrofluidicsystemKeyWords:microfluidicchips;PDMS;lithographyan
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