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Total Synthesis of Thielocin B1 as a Protein-Protein Interaction Inhibitor of PAC3 Homodimer (2015)

Total Synthesis of Thielocin B1 as a Protein-Protein Interaction Inhibitor of PAC3 Homodimer (2015)

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大小：4.63 MB

页数：119页

时间：2019-02-25

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1、SpringerThesesRecognizingOutstandingPh.D.ResearchKosukeOhsawaTotalSynthesisofThielocinB1asaProtein–ProteinInteractionInhibitorofPAC3HomodimerSpringerThesesRecognizingOutstandingPh.D.ResearchAimsandScopeTheseries“SpringerTheses”bringstogetheraselectionoftheverybestPh.D.th

2、esesfromaroundtheworldandacrossthephysicalsciences.Nominatedandendorsedbytworecognizedspecialists,eachpublishedvolumehasbeenselectedforitsscientificexcellenceandthehighimpactofitscontentsforthepertinentfieldofresearch.Forgreateraccessibilitytonon-specialists,thepublishedve

3、rsionsincludeanextendedintroduction,aswellasaforewordbythestudent’ssupervisorexplainingthespecialrelevanceoftheworkforthefield.Asawhole,theserieswillprovideavaluableresourcebothfornewcomerstotheresearchfieldsdescribed,andforotherscientistsseekingdetailedbackgroundinformati

4、ononspecialquestions.Finally,itprovidesanaccrediteddocumentationofthevaluablecontributionsmadebytoday’syoungergenerationofscientists.Thesesareacceptedintotheseriesbyinvitednominationonlyandmustfulfillallofthefollowingcriteria•TheymustbewritteningoodEnglish.•Thetopicshould

5、fallwithintheconfinesofChemistry,Physics,EarthSciences,EngineeringandrelatedinterdisciplinaryfieldssuchasMaterials,Nanoscience,ChemicalEngineering,ComplexSystemsandBiophysics.•Theworkreportedinthethesismustrepresentasignificantscientificadvance.•Ifthethesisincludespreviously

6、publishedmaterial,permissiontoreproducethismustbegainedfromtherespectivecopyrightholder.•Theymusthavebeenexaminedandpassedduringthe12monthspriortonomination.•Eachthesisshouldincludeaforewordbythesupervisoroutliningthesignifi-canceofitscontent.•Thethesesshouldhaveaclearlyd

7、efinedstructureincludinganintroductionaccessibletoscientistsnotexpertinthatparticularfield.Moreinformationaboutthisseriesathttp://www.springer.com/series/8790KosukeOhsawaTotalSynthesisofThielocinB1asaProtein–ProteinInteractionInhibitorofPAC3HomodimerDoctoralThesisacceptedb

8、yTohokuUniversity,Sendai,Japan123AuthorSupervisorDr.KosukeOhsawaProf.TakayukiDoiTohokuUniversityTohokuU

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