络合铜复合材料对大鼠精子功能与形态学影响

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1、华中科技大学硕士学位论文Theeffectsofcopper/low-densitypolyethylenecompositeonthespermfunctionandstructureofratsFamilyPlanningResearchInstitute,TongjiMedicalCollegeHuazhongUniversityofScienceandTechnologyCandidateLiuZhihongTutorProf.XiongChengliangAbstractIntrauterineDevice（IUD）isasecurity，effective，convenient,e

2、conomicalandreversibleforcontraceptionmethod,whichisalsowidelyuseinworld.Inourcountry,therearemanywomentakeintrauterinedevicesasacommonlycontraceptivemethod.Thetotalnumberaccountseightypercentoftotalnumber.Copperintrauterinedevicespersistentlyreleasecopperion,whichhasactivityofantifertility.CopperT3

3、80aisoneofthemosteffectiveintrauterinedevice,butthecomplicationofCopperT380aisserious,suchaspain,hemorrhage,etc.Thecopper/lower-densitypolyethylenecompositeisanewcontrolcontrollablecoppercontainingculture-mediumcomposedofpolyvinylalcohol，silicondioxideandchloratum.Copperionisreleasedthroughthebalanc

4、eofcomplexationratherthancorrosion,whichavoidsthephenomenonofcopperreleasesuddenandviolent,aswellasincreaseeffectivecopperion.PartⅠTheeffectsofthecopper/lower-densitypolyethylenecompositeonthespermfunctionofrats.Objective:Toevaluatetheeffectofthecopper/lower-densitypolyethylenecompositeonmotilityand

5、viabilityofrats.Methods:MaturemaleWistarratspermaredividedintonormalcontrolgroup,V华中科技大学硕士学位论文nonoximolgroupandthecopper/lower-densitypolyethylenecompositegroup.Spernmotilityandviabilityarecomparedamongatdifferenttimepoint.Result:Comparedwithnormalgroups,spermmotilityandviabilityincopper/lower-densi

6、typolyethylenecompositegroupswereobviouslyincreasedatthesametime(P＜0.001).4µg/mlcopper/lower-densitypolyethylenecompositecaninhibitthespermatozoa’smotilityinthirtyminimum.16µg/mlcankillallmotilespermatozoainanhour.Conclusion:Thecopper/lower-densitypolyethylenecompositecaninhibitmotileofspermandkills

7、perminashorttime.Keywords:Copper/lower-densitypolyethylenecomposite;Rat;Sperm;Motility;ViabilityPartⅡTheeffectsofthecopper/lower-densitypolyethylenecompositeonthestructureofsperminrats.Objective:Toobs