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ID:33392007
大小:778.53 KB
页数:49页
时间:2019-02-25
《络合铜复合材料对大鼠精子功能与形态学影响》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、华中科技大学硕士学位论文Theeffectsofcopper/low-densitypolyethylenecompositeonthespermfunctionandstructureofratsFamilyPlanningResearchInstitute,TongjiMedicalCollegeHuazhongUniversityofScienceandTechnologyCandidateLiuZhihongTutorProf.XiongChengliangAbstractIntrauterineDevice(IUD)isasecurity,effective,convenient,e
2、conomicalandreversibleforcontraceptionmethod,whichisalsowidelyuseinworld.Inourcountry,therearemanywomentakeintrauterinedevicesasacommonlycontraceptivemethod.Thetotalnumberaccountseightypercentoftotalnumber.Copperintrauterinedevicespersistentlyreleasecopperion,whichhasactivityofantifertility.CopperT3
3、80aisoneofthemosteffectiveintrauterinedevice,butthecomplicationofCopperT380aisserious,suchaspain,hemorrhage,etc.Thecopper/lower-densitypolyethylenecompositeisanewcontrolcontrollablecoppercontainingculture-mediumcomposedofpolyvinylalcohol,silicondioxideandchloratum.Copperionisreleasedthroughthebalanc
4、eofcomplexationratherthancorrosion,whichavoidsthephenomenonofcopperreleasesuddenandviolent,aswellasincreaseeffectivecopperion.PartⅠTheeffectsofthecopper/lower-densitypolyethylenecompositeonthespermfunctionofrats.Objective:Toevaluatetheeffectofthecopper/lower-densitypolyethylenecompositeonmotilityand
5、viabilityofrats.Methods:MaturemaleWistarratspermaredividedintonormalcontrolgroup,V华中科技大学硕士学位论文nonoximolgroupandthecopper/lower-densitypolyethylenecompositegroup.Spernmotilityandviabilityarecomparedamongatdifferenttimepoint.Result:Comparedwithnormalgroups,spermmotilityandviabilityincopper/lower-densi
6、typolyethylenecompositegroupswereobviouslyincreasedatthesametime(P<0.001).4µg/mlcopper/lower-densitypolyethylenecompositecaninhibitthespermatozoa’smotilityinthirtyminimum.16µg/mlcankillallmotilespermatozoainanhour.Conclusion:Thecopper/lower-densitypolyethylenecompositecaninhibitmotileofspermandkills
7、perminashorttime.Keywords:Copper/lower-densitypolyethylenecomposite;Rat;Sperm;Motility;ViabilityPartⅡTheeffectsofthecopper/lower-densitypolyethylenecompositeonthestructureofsperminrats.Objective:Toobs
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