黄芪注射液足三里穴位注射治疗慢性肾衰竭的临床研究

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1、提要目的：通过系统的临床研究，观察黄芪注射液穴位注射法治疗慢性肾功能衰竭（脾肾亏虚兼湿浊内蕴证）的疗效和不良反应，评价其有效性及安全性，分析其作用机理，为中医治疗慢性肾衰竭提供新的思路与方法。方法：将50例慢性肾功能衰竭（脾肾亏虚兼湿浊内蕴证）患者随机分成2组，治疗组（常规治疗+穴位注射组）和对照组（常规治疗组）。对照组予以常规中西医结合治疗,治疗组在常规治疗的基础上加用穴位注射疗法，疗程8周。治疗前后分别收集两组患者临床症状、体征、实验室检查等资料并作出疗效及安全性评价。结果：临床研究：治疗组显效率16%，总有效率92％；对照组显效

2、率8％，总有效率72％，治疗组在临床控制率及总有效率方面均优于对照组，但无显著差异性（P>0.05）。结论：在常规治疗基础上加用穴位注射疗法对慢性肾功能衰竭脾肾亏虚兼湿浊内蕴证患者的疗效优于单纯常规治疗，且不增加副作用。其作用机理主要是通过穴位和药物的共同作用，通过局部和整体的协同调节，而达到治疗作用的。关键词慢性肾功能衰竭；穴位注射疗法；疗效及副作用；作用机理TheClinicalResearchOfInjectingHuangqiInThePointOnTreatingChronicRenalFailureSpeciality:M

3、edicineofTCMAuthor:lishuangTutor:Prof.MiJieAbstractObjective:Thisstudyaimstoobserveandconfirmthecurativeeffect,sideeffectsanduntowardeffectofInjectingHuangqiinthepointontreatingCRFofthespleen-kidneydeficiencytype.Assessingthesafetyandeffectiveness,thispaperanalyzesandex

4、poundsitstreatmentsmechanismoftraditionalChinesemedicineclinicaltreatmentforchronicrenalfailurewithnewwaysandnewmeans.Method:50casesofchronicrenalfailurepatientswererandomlydividedintotwogroups,trialgroup(pointinjectiongroup)andthecontrolgroup(conventionaltreatmentgroup

5、),thecontrolgroupgavetraditionalChineseandwesternmedicinetreatment(includingwesternmedicinetherapyandconventionaloralmedicine),patientsinthecontrolgrouptreatmentbasedontopointinjectiontherapy.Allofthemwereundertreatmentfor8weeks.Theobservationweretheclinicalsymptoms,sig

6、nsofchangeoflaboratoryexamination.Results:Clinicalresearch:thetrialcontrolratesby16.67%,thetotaleffectiverateof86.67%;Thecontrolgroupclinicalcontrolratesby6.7%,thetotaleffectiverate53.33%,.Thetwogroupsofcomparisonshavesignificantdifference(P<0.01).Researchshowsthat:poin

7、tinjectiondoesbetterinimprovingtherapychronicrenalfailure(spleenandkidneydeficiencysyndrome)syndrome,improvingthehemoglobinlevels,lowerurineproteinquantitativeandendogenouscreatinineclearance,serumcreatinine,bloodureanitrogenregulation.Ithasapparentcurativeeffect,andmor

8、esafety.TheadversereactionrateislowerConclusion:Pointinjectiontreatmentsforchronicrenalfailurehasdefiniteeffec