初发graves病对骨代谢的影响

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1、万方数据中文摘要实验组OST平均值(48．62+19．92)ng／ml，对照组OST平均值(14．02士3．75)ng／ml，尸值

2、维生素D3平均值(17．60+7．85)ng／ml，对照组25一羟维生素D3平均值(23．554-7．87)ng／ml，P值

3、ABSTRACTPurpose：ToobservethechangeofbonemetabolismindexesofinitialGravesdiseasepatients，tolearntheeffectsofinitialGravesdiseaseonbonemetabolism，toprovideclinicalevidenceforcorrectingabnormalitiesofbonemetabolism．Method：Choose45initialhyperthyroidismpatients，whohave

4、receivedtreatmentinourhospitalbetweenApr．2014toSept．2014，assubjects，while44healthypeoplewithsimilarage，professionandgenderarechosenasthecomparativegroup．Measurethethyroidfunction(FT3、FT4、TSH)andrelavantantibodies(TRAb、TPOAb)withChemiluminescenceparticlesimmunoassay

5、sinthesameseason．Measurebloodcalciumwithionselectiveelectrodemethod．End—pointenzymaticbloodphosphorus．Measure(OST)and(p·CTX)withelectrochemiluminescence．Measure25一dihydroxyvitaminD3withHPLC—MS／MS．MakestatisticalanalasisontheresultswithSPSSl6．O．UsettestandMann·Whitn

6、eyUnon—parametrictesttodoanalysisofmeasurementdata．P<0．05，thereisstatisticalsignifiCanCe．Result：1Thyroidfunctiontest：FT3andFT4ofhyperthyroidismpatientsarevisiblyhigherthanthatofthehealthypeople，whileTSHisvisiblylower．TheaveragevalueofFT3(freetriiodothyronine)ofhype

7、rthyroidismpatientis(23．51士14。63)pmol／L，whiletheaveragevalueofFT4(freethyroxine)is(41．08114．03)pmol／L，comparedwiththeaveragevalueofFT3(4．321O．51)pmol／LandFT4(15．71士1．82)pmol／Lofthehealthypeople．Pvalueislowerthan0．001．hyperthyroidismpatients’averageTSHis(O．003士O．013

8、)uIU／ml，comparedwiththeaverageTSH(2．132士1．027)ulU／mlofhealthypeople．PvalueislowerthanO．001．2Thyroid’Srelavantantibodiestest：hyperthyroidismpatien