丹栀逍遥散对桥本甲亢肝郁脾虚挟热证的临床干预与研究

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1、提要目的：观察丹栀逍遥散对桥本甲亢的临床治疗疗效。方法：将符合纳入标准的桥本甲亢患者60例，采用随机的方法分成两组，观察组30例，对照组30例。两组均进行饮食、运动方面的基础治疗，在此基础治疗上，对照组加服他巴唑和心得安治疗，观察组加服中药丹栀逍遥散加减，观察周期为4周。观察治疗前后患者临床症状、体征及游离三碘甲状腺原氨酸(FT3)、游离四碘甲状腺原氨酸(FT4)、促甲状腺激素（TSH）、甲状腺球蛋白抗体（TGAb）、甲状腺过氧化物酶自身抗体（TPO-Ab）、白细胞等临床实验指标的变化，并将两组的综合疗效进行比较。结果：经过4周的观察后，中药观察组在改善患者临床症状、体征方面

2、优于西药对照组，并且可以降低甲减的发生率。结论：丹栀逍遥散加减对桥本甲亢有良好的治疗作用，能较好的改善患者的临床症状，且副作用少。提示中医药辨证在治疗桥本甲亢并扼制其进一步发展成甲减方面具有明显优势。关键词桥本甲亢；肝郁脾虚挟热；丹栀逍遥散；临床干预ClinicalObservationofTheEffectofDanZhiXiaoYaoDecoctiononThePatientsWithLiverstagnationandspleendeficiencyandheatofhashimoto’sthyroiditisandHyperthyroidismSpecialty:TC

3、M-EndocrinologyAuthor:TangYalanTutor:ProfessorZhaoQuanlinAbstractObjective:ToinvestigatetheclinicalefficacyofDanZhiXiaoYaoDecoctionintreatingLiverstagnationandspleendeficiencyandheatofHashimoto’sthyroiditis(HT)andHyperthyroidismMethods:Those60DiabeticDiarrheas,whohadbeenchosenintothisclinic

4、alresearch,weredividedintotwogroupsatrandom,theobservationgroupandthecontrastgroup.Eachgrouphad30cases.Thetwogroupswerediet,exerciseofthefoundationtreatmentBasedonthetreatment，thepatientsofcontrastgroupweretreatedwithwesternmedicineMethimazoleandPropranolol,thepatientsofobservationgrouptook

5、theDanZhiXiaoYaoDecoction.Fourweekswereacourseoftreatment.Results:Aftertheinvestigationof4weeks,theresesrchshowedthatthetreatmentoftraditionalmedicinewasmoreeffectiveonimprovingsignsandsymptomsofthepatientsthanwesternmedicineandalsocouldreducetherateof.HypothyroidismConclusion:DanZhiXiaoYao

6、DecoctionhasagoodtherapeuticeffectontreatingtheHashimoto’sthyroiditis(HT)andHyperthyroidism.itcouldobviouslyimprovetheclinicalsyndromeofthepatients.ItalsoconfirmedthattraditionalChinesemedicinehadconsiderableclinicalvalueandwidestforegroundintreatingHTandHyperthyroidismandpreventingtherateo

7、fHypothyroidism.KeywordsHashimoto’sthyroiditisandHyperthyroidism;Liverstagnationandspleendeficiencyandheat;DanZhiXiaoYaoDecoction;Clinicaleffect目录引言..........................................................................................................