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1、SpringerThesesRecognizingOutstandingPh.D.ResearchSosukeItoInformationThermodynamicsonCausalNetworksanditsApplicationtoBiochemicalSignalTransductionSpringerThesesRecognizingOutstandingPh.D.ResearchAimsandScopeTheseries“SpringerTheses”bringstogetheraselectiono
2、ftheverybestPh.D.thesesfromaroundtheworldandacrossthephysicalsciences.Nominatedandendorsedbytworecognizedspecialists,eachpublishedvolumehasbeenselectedforitsscientificexcellenceandthehighimpactofitscontentsforthepertinentfieldofresearch.Forgreateraccessibility
3、tonon-specialists,thepublishedversionsincludeanextendedintroduction,aswellasaforewordbythestudent’ssupervisorexplainingthespecialrelevanceoftheworkforthefield.Asawhole,theserieswillprovideavaluableresourcebothfornewcomerstotheresearchfieldsdescribed,andforothe
4、rscientistsseekingdetailedbackgroundinformationonspecialquestions.Finally,itprovidesanaccrediteddocumentationofthevaluablecontributionsmadebytoday’syoungergenerationofscientists.Thesesareacceptedintotheseriesbyinvitednominationonlyandmustfulfillallofthefollow
5、ingcriteria•TheymustbewritteningoodEnglish.•ThetopicshouldfallwithintheconfinesofChemistry,Physics,EarthSciences,EngineeringandrelatedinterdisciplinaryfieldssuchasMaterials,Nanoscience,ChemicalEngineering,ComplexSystemsandBiophysics.•Theworkreportedinthethesis
6、mustrepresentasignificantscientificadvance.•Ifthethesisincludespreviouslypublishedmaterial,permissiontoreproducethismustbegainedfromtherespectivecopyrightholder.•Theymusthavebeenexaminedandpassedduringthe12monthspriortonomination.•Eachthesisshouldincludeaforew
7、ordbythesupervisoroutliningthesignifi-canceofitscontent.•Thethesesshouldhaveaclearlydefinedstructureincludinganintroductionaccessibletoscientistsnotexpertinthatparticularfield.Moreinformationaboutthisseriesathttp://www.springer.com/series/8790SosukeItoInformati
8、onThermodynamicsonCausalNetworksanditsApplicationtoBiochemicalSignalTransductionDoctoralThesisacceptedbyTheUniversityofTokyo,Tokyo,Japan123AuthorSupervisorDr.SosukeItoProf.MasakiSanoDepartmentof