加味黄芪建中汤治疗复发性口腔溃疡(脾肾阳虚证)的临床疗效观察

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1、学位论文加昧黄芪建中汤治疗复发性口腔溃疡(脾肾阳虚证)的临床疗效观察刘誉华指导教师姓名：梁超主任医师申请学位级别：亟±专业名称：(主匡囱型堂2膣置瘗疸的虫匡适迨趣往兰硒塞论文提交时间：2012-3-10论文答辩时间：2012—5—20二O一二年五月盛型史医药太堂亟±论塞f幽卿舢删㈣删删删舢Y2520058中文摘要目的：通过加味黄芪建中汤治疗复发性口腔溃疡(脾肾阳虚证)的临床试验研究，观察临床疗效。方法：将符合诊断标准的60例病人随机分为治疗组和对照组，治疗组和对照组各30例。两组病例资料、治疗前症状积分等经统计学处理没有显著差异，

2、有可比性。治疗组以加味黄芪建中汤治疗，对照组治疗以附子理中丸治疗。比较治疗前后口腔溃疡的变化情况。结果：(1)近期疗效比较：治疗组总有效率为93．3％，对照组总有效率为90％，无显著性差异，两组疗效相当。远期疗效(6个月)比较：治疗组总有效率96．6％，对照组80％，两组总疗效比较有显著性差异(p

3、虚证)有显著疗效，溃疡愈合期缩短，疼痛减少，溃疡复发间隔期延长，溃疡数目减少。治疗组的近期疗效与对照组相当，但其远期疗效明显优于对照组。关键词：复发性口腔溃疡，加味黄芪建中汤，附子理中丸ABSTRACTobjective：ThroughtheclinicalexperimenttrailsonmodifiedHuangQiJianZhongDecoctionintreatingrecurrentoralulcerwithyang-deficiencysyndromeofspleenandkidney,weobservedthecl

4、inicalcurativeeffect．Methods：The60casegofpatientswhoallaccordwiththediagnosticcriteriawererandomlydividedintothetreatmentgroupandcontrolgroup．Thetreatmentgrouphas30cases，whilethecontrolgroupalsohas30cases．Thegenerainformationandpreviousaccumulatedscoresofsymptomsbetwe

5、enthetwogroupsarebasiclythesame．Bystatisticalprocessed，thereisnosignificantdifferenceofmeaningbetweenthetwogroups，SOtheycanbecomparabled．ThetreatmentgroupusesmodifiedHuangQiJianZhongDecoction，whilethecontrolgroupusesFuZiLiZhongPills．WeComparetheclinicalsymptomsbeforea

6、ndaftertreatmen．Results：(1)Shorttermeffect：thetotaleffectrateofthetreatmentgroupis93．3％andthetotaleffectrateofthecontrolgroupis90％，andthetotalcurativeeffectbetweenthetwogroupshasnoproniminentdifference．Longtermeffect(sixmonthes)：thetotaleffectrateofthetreatmentgroupis

7、96．6％andthetotaleffectrateofthecontrolgroupis80％，andthetotolcurativeeffectbetweenthetwogroupshasprominentdifference(p<0．05)．Thetreatmentgroupissuperiortocontrolgroup．L0ngtermeffect(oneye砌：thetotaleffectrateofthetreatmentgroupis96．6％andthetotaleffectrateofthecontrolgro

8、upis76．6％，andthetotolcurativeeffectbetweenthetwogroupshasprominentdifference0<0．05)．Thetreatmentgroupissuperiortocontrolgrou