口服山莨菪碱治疗婴幼儿轮状病毒肠炎疗效观察-儿科医学论文

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1、口服山莨菪碱治疗婴幼儿轮状病毒肠炎疗效观察-儿科医学论文口服山莨菪碱治疗婴幼儿轮状病毒肠炎疗效观察黄　琳　刘　杰　刘长青邵阳医学高等专科学校附属医院儿科,湖南邵阳　422000[摘要]目的探讨观察口服山莨菪碱辅助婴幼儿轮状病毒肠炎的临床疗效。方法222例患者随机分成两组，对照组(114例)采用补液、抗病毒、口服思密达、双歧杆菌、合理饮食、对症治疗;治疗组(108例)在上述治疗基础上加口服山莨菪碱片0.1~0.2mg/(kg·次),2次/d},两组疗程均为5~7d。结果治疗组108例中显效24例(22.2%),有效69例(63.9%),无效1

2、5例(13.9%),总有效率93%;对照组114例中,显效27例(23.7%),有效45例(39.5%),无效42例(36.8%),总有效率63.2%,治疗组与对照组比较差异有统计学意义(P0.05)。结论口服山莨菪碱片治疗婴幼儿轮状病毒肠炎有明显疗效。关键词山莨菪碱；轮状病毒；肠炎[中图分类号]R4[文献标识码]A[文章编号]1674-0742(2014)03(b)-0005-02ObservationontheEfficacyofOralAnisodamineintheTreatmentofInfantileRotavirusEnter

3、itisHUANGLinLIUJieLIUChangqingDepartmentofPediatrics,TheAffiliatedHospitalofShaoyangMedicalCollege,Shaoyang,HunanProvince,422000,China[Abstract]ObjectiveToobservetheclinicalcurativeeffectoftakinganisodamineorallyinthetreatmentofinfantileduovirusenteritis.Methods222casesofp

4、atientswererandomlydividedintotwogroups,114casesinthecontrolgroupweregiventhetreatmentsuchasfluidinfusion,antiviraltreatment,takingsmectaandbifidobacteriumorally,reasonabledietandsymptomatictreatment.Andtheother108casesinthetreatmentgroupweregivenanisodamine{(0.1mg-0.2mg)/

5、kgtime,bid}orallyonthebasisofthetreatmentgiventothecontrolgroup.Thetreatmentcourseoftwogroupswas5-7days.ResultsOfthe108casesinthetreatmentgroup,excellencein24cases(22.2%),validityin69cases(63.9%),invalidin15cases(13.9%),thetotaleffectiverateis93%.Ofthe114casesinthecontrolg

6、roup,excellencein27cases(23.7%),validityin45cases(39.5%),invalidin42cases(36.8%),thetotaleffectiverateis63.2%.Thereisstatisticallysignificantdiscrepancybetweenthecontrolgroupandthetreatmentgroup(P0.005).ConclusionTakinganisodamineorallyhassignificantcurativeeffectinthetrea

7、tmentofinfantilerotavirusenteritis.[Keywords]Anisodamine;Duovirus;Enteritis[作者简介]黄琳(1980.11-)，女，湖南邵阳人，本科，主治医师，研究方向：儿科临床与教学，邮?aclass=“__cf_email__”href=“/cdn-cgi/l/email-protection”data-cfemail=“5db9fee72b34323134336c6c6b1d6c6b6e733e3230”>[emailprotected]。婴幼儿轮状病毒肠炎是婴幼儿常见病,主

8、要侵犯6个月～2岁的婴幼儿,主要表现为呕吐、腹泻及高热,常导致脱水、酸中毒、代谢紊乱及休克而威胁生命，抗生素治疗无效。为缩短病程，减轻病人痛苦，为探讨观察口服山莨菪碱辅助婴幼儿轮