锥束ct系统几何校正方法-(6226)

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1、摘要r<100μm。该数值已达到并高于项目初始目标所设定的150μm标准。最后，使用经过几何校正的锥束CT系统对鸡爪骨骼结构进行三维重建，从重建图像中可清晰地观察到每块骨骼的形态结构，甚至骨骼表面微小凹凸。对海螺、皮皮虾、鲫鱼的三维重建结果也显示，系统的重建图像空间分辨率比较高。实验证明该方法校正精度很高，能够满足实际工程需要。关键词锥束CT几何校正模体高精度IIAbstractAbstractThispaper’sworkisonthebaseofMedicalMolecularImagingSystemofSmallAnimal,whichisaproje

2、ctaimingatcombiningfourimagingmodulesintooneintegratedimagingsystem.ThefourmodulesincludeCT(ComputedTomography),Micro-PET(PositronEmissionTomography),SPECT(Single-PhotonEmissionComputedTomography)andFMT(FluorescenceMolecularTomography).Thefocusofthispaperisthegeometriccalibrationmet

3、hodoftheCTpart,aCBCT(ConeBeamCT).CBCTisalsoknownasMicro-CTorsmallanimalCT,andit’sananatomicalorstructuralimagingtechniquewhileitsimagingprincipleisbasedonX-rayattenuation.CBCThasadvantagesofnon-invasiveandin-vivoimaging,especiallythehigh3Dreconstructionresolutionatthemicronscale,whi

4、chmakeitgainsextensiveattentionandrapiddevelopmentsinceborn,andhasbecomeanimportantresearchmeaningenetherapy,cancerresearch,drugdevelopmentandmaterialsscience,industrialNon-DestructiveTestingarea.Inthispaper,adedicatedcalibrationphantomwasdesignedtocalibratethegeometricmisalignmento

5、ftheCBCTsystem.Thefeaturesofthephantom’sprojectswereusedtoestimatethegeometricmisalignmentparametersofthesystemandthenadjustthedeviceswhichincludestheX-raysourceandtheflatpaneldetectortorightpositions.ThepurposeofthismethodistominimumthegeometricmisalignmentoftheCBCTsystemasbestaspo

6、ssible.ThispaperintroducedthehighperformanceofCBCTanditsimportantroleinmultipleareas,thenthegenerationofgeometricmisalignmentofCBCTsystemandthedegradationitcausedonthequalityofreconstructionimages.TheresearchstatusathomeandabroadofCBCTgeometriccalibrationhasbeenpresentedalso.Theoper

7、atingprinciple,systemconstitutionofCBCTandmainperformanceofdevicessuchasX-raysourceandflatpaneldetectorhasbeendiscussedthen,alsothetheoryofFDKreconstructionalgorithmanditsdemandingrequirementstoCBCTsystemgeometry.IIIAbstractThenthispaperanalyzedthegeometriccharacteristicsofCBCTsyste

8、mwithaverticalstruc