壮医药线点灸对糖尿病性胃轻瘫模型大鼠的胃肠推进率、血糖与胃窦cajal间质细胞的影响

《壮医药线点灸对糖尿病性胃轻瘫模型大鼠的胃肠推进率、血糖与胃窦cajal间质细胞的影响》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。

1、关键词：壮医药线点灸,糖尿病性胃轻瘫,胃肠推进率,血糖,Cajal间质细胞ResearchontheeffectofZhuangmedicinemedicatedthreadmoxibustiononrateofgastrointestinalpropulsionandBloodglucoseandinterstitialcellsofCajalingastricantrumofdiabeticgastroparesisratsABSTRACTObjective：ToobservetheeffectofZhuangmedicin

2、emedicatedthreadmoxibustiontherapyonrateofgastrointestinalpropulsionandBloodglucoseandinterstitialcellsofCajal（ICC)ingastricantrumofdiabeticgastroparesis（DGP)rats,soastoinvestigatetheirmechanismunderlyingimprovingDGP.Methods：CleanSpregue-Dawley（SD)malerats（n=90)werer

3、andomlydividedinto3groups（eachn=30):control,modelandtreatmentgroups,Ratsinthemodelgroupandtreatmentgroupwereintraperitonealinjectedwithstreptozotocin（STZ).TreatmentgroupwasappliedtoZhuangmedicinemedicatedthreadmoxibustiontherapyfor3weeksafterDGPmodelwasdetermineestab

4、lishedin10weeks.Eachgroupwasmeasuredforthebloodglucoseandrateofgastrointestinalpropulsionandthetissuespecimenswereanalyzedbyimmunohistochemicalassayforc-kitpositiveICCingastricantrum.Results：（1）SomeratsinthetreatmentgrouphaddifferentreliefinDMsymptomaftertreatment，ga

5、iningweight，increasingfeeding，formerdefecate，shiniercoat.（2）Therateofgastrointestinalpropulsionwassignificantlyhigherinthetreatmentgroupthanthatinthemodelgroup（P<0.01).（3）Thebloodglucosewassignificantlylowerinthetreatmentgroupthanthatinthetreatmentgroupbeforetreatmen

6、t（P<0.05)andthemodelgroupaftertreatment（P<0.05).（4）Immunohistochemistryshowedthattherateofc-kitpositivecellwassignificantlyhigherinthetreatmentgroupthanthatinthemodelgroup（P<0.01).Conclusion：TheZhuangmedicinemedicatedthreadmoxibustiontherapycanimprovetheexpressionoft

7、hec-kitinICC,recoverthenormalfunctionofICCandincreasetherateofgastrointestinalpropulsion,reducethebloodglucosetoacertainextent.Keywords：Zhuangmedicinemedicatedthreadmoxibustion,Diabeticgastroparesis,Rateofgastrointestinalpropulsion,Bloodglucose;InterstitialcellsofCaj

8、al目录引言....................................................1正文....................................................31实验材料............