梗阻性黄疸大鼠肠系膜微循环的实验分析

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1、荚文摘要——．——一—··————————一theabdomen，laparotomywasperfbrmed．Anincisioninthemidstofabdomen(about1．5cminlength)wasdone，choledoehUSwasdissociatedincontrolgroup．whilebomcholedochUSdissocimionandcholedochusdualligationwereperformedinobstructivejaundicegroup．3．Observingmethodsformesentericmicrocircu

2、lation：openeduptheabdomenandileocecaljunctionwasfound，thenthemesenteryofileumWasputoutandanareawithlessfatWasselectedastheobservingarea．ThemesenterythatwasusedaSobservingareawasspreadontheirrigatingandflowingbox，fullyexposedmesenterymicrocirculationWasobservedwithmicrocirculatorymicroscope

3、andvideotapedimagesanalyzingsystemanditsresultsweretakendown，4．TimephuseandIndex：Bothgroupsareobservedoneday,threedayandsevendayafterobstructive{aundice．Observingindexesincludedmicrovasculardistinctness，diameter,flowstate，flowvelocity,congregationofelythrocytes，adherenceofleukocytes，hemorr

4、hageandexudation，5．statisticalanalysis：Differenttypesofdataweredealtwiflacorrespondingstatisticalmethodsbyusingspss11．5software．CriterionfortestingofsignificanceWasO．05．Results：1．morphologicchangesofmesentericmicrocireulationateachtimephasesinobstructivejaundicegroup1．1Distinctness：microve

5、sselsweredistinctateverytimephasesinobstructivejaundicegroup，whichWasnotdifferentfromcontrolgroup(p>0．05)．英文摘要1．2Diametersofvessels：Thediametersofcapillaryvesselsateverytimephasesinobstructivejaundicegroupincreased，andshowedagraduallydilatingtendency,whichwasdifferentfromthatofcontrolgroup

6、(p<0．05)；venulesduringthistimeconstractedatthebeginning，thenimprovedtonormal，anddilatedafterwards．Comparedwithcontrolgroup，differenceWassignificant(p<0．05)onedayandsevendayafterobstructive，iaundice，whiledifferenceWasnotsignificant(p>0．05)threedayafterobstructivejaundice．2．Changesinmesenter

7、icmicrocirculatoryflowstateofeverytimephasesinobstructivejaundicegroup．2．1velocityofbloodflow：Bothcapillaryandvenularbloodflowvelocityofeverytimephasesinobstructivejaundicegroupdecreasedandshowedagraduallydecreasingtendency，whichWasdifferentfromcontrolgroup(p<