电针对急性脑梗死大鼠缺血脑组织单胺类递质影响的实验分析

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1、湖北中医学院2007届硕士研究生毕业论文ABSTRACTobieetive：Cerebrovasculardiseaseisacommonandfrequencyoccurdngillness,diseasewiththefeatureofhi。ghdiseaseincidence,highmortalityrateandhighmutilationrate．Agreatdealofclinicalresearchesandempiricalstudiesshowthatacupuncturehasunique

2、curativeeffectonthisdisease．Toappm卵hits’mechanismofaction,wecarriedoutthisexperiment．n地SDratswereobjectsinthisexperiment．Wemaderatfocalcerebralischemiamodelwithmiddlecerebralarteryocclusionusingathreadblocktechnique．Wegaveamarkoftheneurologicimpairmentinrata

3、nddetectedthecontentsofNE、DA、5-HTinrats’ischemiabraintissuebyelectro-acupunetme(EA)onBaihui(DU20)andShmgou(DU26)acupoint．Inthisway,wea∞扛yingtoexplorethemechanismofacupuncturetherapyinacutecerebralinfarction．Methods：40SDratsw船selected．Eachrat’Sbodyweightwasfr

4、om1809to2309．Theywel"erandomlydividedintofourgroups，eachgroupwith10rats『：normalgroup，shamoperationgroup，modelgroupandmodelEAgroup．Thereare10ineachgroup．Normalgroupmtswerenotprovidedtreatment．Modelgroupweremadefocalcerebralisehemiamodelwithmiddecerebralartery

5、occlusionusingathreadblocktechnique．ModelEAgroupWastreatedbyEAonBaihuiandShuigouwithcontinuouswaveof100vicesperminuteflequencyaftertheratswokeup．11抢treatmentcontinuedforfivedays，onevicefor30minutesperday．№Wemarkedofthencurologicimpairmentintheratsanddetected

6、theconteIItsofNE、DA、5-HTinrats’ischemiabraintissue．Results：1．focalcerebralischemiaratswithdghtmiddlecerebralarteryocclusionusingathreadblocktechniquehadsoftiedegreebehaviordisordertosomedegree，withPowerlesspalpebrafrontalis,Icvo-circlingobjectivesigns，andthe

7、irleftforefootflectioncouldn’texpandthomughly．T拭sshowedthattheCImodelsweremadesucceeded．AftertreatedbyEA,neurologicdefectobjectivesignsofratimprovedobviously,Comparedwithmodelgroup，thereWassignificantdifferenceaP

8、lgroup,thecontentsofNE、DAinrats’ischcmiabraintissueinmodelgroupincreasedgreaflyOa