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1、中图分类号：R24；R246；R246.7硕士学位论文火针治疗痤疮技术规范化方案的临床评价研究院（系）、所中西医结合学院研究生姓名王莹学科、专业针灸推拿学导师姓名黄蜀主任医师二Ο一二年四月目录1耳尖刺血配艾灸治疗痤疮后色素沉着的临床研究„„„„„„11.1中文摘要„„„„„„„„„„„„„„„„„„„„„„„11.2英文摘要„„„„„„„„„„„„„„„„„„„„„„„31.3前言„„„„„„„„„„„„„„„„„„„„„„„„„61.4临床研究„„„„„„„„„„„„„„„„„„„„„„„81.5结果„„„„„„„„„„„„„„„„„„„„„„„„„19
2、1.6讨论„„„„„„„„„„„„„„„„„„„„„„„„„271.7结论„„„„„„„„„„„„„„„„„„„„„„„„„331.8参考文献„„„„„„„„„„„„„„„„„„„„„„„342致谢„„„„„„„„„„„„„„„„„„„„„„„„„363综述„„„„„„„„„„„„„„„„„„„„„„„„„37火针治疗痤疮技术规范化方案的临床评价研究中文摘要目的：痤疮是一种常见的损容性疾病，约占皮肤科门诊量的30%，是青春期常见的一种毛囊皮脂腺慢性炎症性皮肤病，好发于颜面部、胸背部，可形成粉刺、丘疹、脓疱、结节、囊肿等严重损害,易反复发作，重者常伴有瘢痕形
3、成，严重影响美观，甚至出现自卑、焦虑、抑郁、暴躁等心理异常。本研究旨在观察火针治疗痤疮的临床疗效，为肯定火针治疗痤疮的临床疗效提供了可信度高的依据，制定严谨的科学设计和评价方法，对火针治疗痤疮的方案进行临床研究，对形成操作规范方案及指南具有临床指导意义和推广意义。方法：（1）本临床研究采用多中心、随机对照研究，将入选的病例分为两组，每组最少需样本例数n=117，两组最少需总例数N=234，考虑脱落与失访原因再扩大20%，治疗组、对照组病例均按1：1设立，共260例。并将全部入选患者按就诊顺序编号，采用SPSS统计软件产生随机分配方案。将随机分配方案隐藏（装
4、入按序列编码的、密封的、不透光的信封中）分配治疗，并作登记。（2）治疗组采用火针治疗，每5天1次，共治疗4次。对照组采用西医疗法，早晚各1次，连续20天。（3）观察结束后将所有数据量化处理，运用统计软件SPSS19.0进行统计分析。结果：（1）本研究采用火针治疗结节囊肿性痤疮，结果显示临床疗效肯定（痊愈率16.8%,愈显率79.2%，有效率96.8%），其痊愈率、愈显率、有效率均明显高于西药组的治疗效果（痊愈率0.0%,愈显率15.2%，有效率87.8%），P=0.000。3个中心的疗效率比较无显著差异，P>0.05。（2）2种治疗方案都对粉刺、丘疹、脓疱
5、、囊肿、结节等皮损，对肿痛、颜色、油腻等评分有显著改善，在改善程度上，以火针疗法更为明显。P=0.000。（3）两种治疗方案对各型痤疮的起效时间上，以火针疗法为优，起效时间快于药物组。（4）两种治疗方案均无明显不良反应。结论：本研究证实了该技术治疗各种类型痤疮具有皮损消退迅速、清除病灶彻底、有效控制复发；技术安全可控、操作规范、实用性强，易于推广使用等优点。为肯定火针治疗痤疮的临床疗效提供了可信度高的依据。关键词：痤疮火针临床评价Clinicalevaluationofthestandardizationprogramforfire-needletreat
6、mentofAcneAbstract:Objective:Acneisacommonlosscapacitivedisease,accountsforabout30%oftheMenZhenLiangdermatologist,adolescenceisacommonchronicinflammatoryskindiseasehairfolliclesebaceousglands,goodhairatfaceministry,chestback,canformacne,papula,pustular,nodules,cystseriousdamage,ea
7、sytobreakoutrepeatedly,thepersonthatweighisoftenaccompaniedbyscarring,seriouseffectisbeautiful,appeareveninferiority,anxiety,depression,short-temperednessandabnormalpsychology.ThisstudyaimstoobservetheclinicalefficacyofHuoZhentreatacne,forsureHuoZhentheclinicalcurativeeffectoftrea
8、tingacneprovidesthebasisforthehig
