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时间:2019-02-17
《控制性促排卵对卵泡期血清孕激素水平的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、遵义医学院硕士学位论文控制性促排卵对卵泡期血清孕激素水平的影响姓名:钱正利申请学位级别:硕士专业:妇产科学指导教师:谭晓珊20120428遵义医学院硕士学位论文控制性促排卵对卵泡期血清孕激素水平的影响中文摘要目的:探讨控制性促排卵(COS)对卵泡期血清P水平的影响以及COS周期卵泡期血清P异常升高与同期自然周期P水平的关系。方法:以2010年6月至2011年6月在遵义医学院附属医院生殖中心接受IVF.盯治疗(142例,142周期)及自然周期排卵监测(97例,97周期)不孕患者作为研究对象,其中52例在完成自然周期排卵监测后再接受IVF.盯
2、治疗。采用放射免疫分析法检测患者早、中、晚卵泡期血清P浓度。结果:COS周期卵泡期血清孕酮浓度的变化趋势与自然周期相同。随着卵泡生长发育成熟,血清P浓度自早卵泡期至晚卵泡期均呈逐渐上升的趋势(分别为F=66.531,P3、在其COS周期中仅8例重复发生血清P的异常升高,而COS周期中有13例血清P异常升高的患者在其前自然周期中血清P浓度均未超过界值(x。=0.17,尸>0.05)。结论:COS周期中卵泡期血清P水平的变化规律与自然周期相同。控制性促排卵药物的应用不改变其血清P水平的变化趋势,也不增加卵泡期血清P异常升高的发生率。自然周期卵泡期同样存在血清P异常升高的现象。自然周期卵泡期血清P异常升高与COS周期血清P异常升高之间未见明确关系。关键词:控制性促排卵体外受精.胚胎移植孕激素卵泡期遵义医学院硕士学位论文控制性促排卵对卵泡期血清孕激素水平的影响Ab4、stractObjective:Toevaluatetheimpactofthecontrolledovarianstimulation(COS)ontheserumprogesteronelevelinfollicularphase,andtoexploretherelationshipbetweentheserumprogesteronelevelelevatedabnormallyinthefollicularphaseofCOScycleandtheserumprogesteronelevelinthecorrespondingp5、eriodofnaturalcycleMethods:142casesofIVFperformedand97casesofpatientsacceptedmonitoringovulationinnaturalcyclewereanalyzedinthisstudy,thereinto,52ofthe97caseswereperformedIVF—ETafterthecompletionofthemonitoringovulation.TheserumprogesteronelevelswereanalysedbyradiolmmunOa6、ssay.Result:ThechangingtrendoftheserumprogesteronelevelwassimilarinCOScycleandinnaturalcycle.TheserumprogesteronelevelsshowedgraduallyincreasingtrendfromtheearlyfolliculartotheatefollicularphaseinthenaturalcycleandinCOScycle(F=66.531,P<0.01andF=59.475,P<0.01),andapositive7、correlationwasshowedbetweentheserumprogesteronelevelandthefolliclegrowthratefP<0.oz).Aphenomenonoftheserumprogesteronelevelelevatedabnormallywasobservedinthelatefollicularperiodofnaturalcycle(29/97).Theselfcontrolledstudyof52casesshowedthencidenceoftheserumprogesteronelev8、elelevatedabnormallywasrespectively34.62%(18/52)and40.38%(21/52)innaturalcycleandCOScycle.18case
3、在其COS周期中仅8例重复发生血清P的异常升高,而COS周期中有13例血清P异常升高的患者在其前自然周期中血清P浓度均未超过界值(x。=0.17,尸>0.05)。结论:COS周期中卵泡期血清P水平的变化规律与自然周期相同。控制性促排卵药物的应用不改变其血清P水平的变化趋势,也不增加卵泡期血清P异常升高的发生率。自然周期卵泡期同样存在血清P异常升高的现象。自然周期卵泡期血清P异常升高与COS周期血清P异常升高之间未见明确关系。关键词:控制性促排卵体外受精.胚胎移植孕激素卵泡期遵义医学院硕士学位论文控制性促排卵对卵泡期血清孕激素水平的影响Ab
4、stractObjective:Toevaluatetheimpactofthecontrolledovarianstimulation(COS)ontheserumprogesteronelevelinfollicularphase,andtoexploretherelationshipbetweentheserumprogesteronelevelelevatedabnormallyinthefollicularphaseofCOScycleandtheserumprogesteronelevelinthecorrespondingp
5、eriodofnaturalcycleMethods:142casesofIVFperformedand97casesofpatientsacceptedmonitoringovulationinnaturalcyclewereanalyzedinthisstudy,thereinto,52ofthe97caseswereperformedIVF—ETafterthecompletionofthemonitoringovulation.TheserumprogesteronelevelswereanalysedbyradiolmmunOa
6、ssay.Result:ThechangingtrendoftheserumprogesteronelevelwassimilarinCOScycleandinnaturalcycle.TheserumprogesteronelevelsshowedgraduallyincreasingtrendfromtheearlyfolliculartotheatefollicularphaseinthenaturalcycleandinCOScycle(F=66.531,P<0.01andF=59.475,P<0.01),andapositive
7、correlationwasshowedbetweentheserumprogesteronelevelandthefolliclegrowthratefP<0.oz).Aphenomenonoftheserumprogesteronelevelelevatedabnormallywasobservedinthelatefollicularperiodofnaturalcycle(29/97).Theselfcontrolledstudyof52casesshowedthencidenceoftheserumprogesteronelev
8、elelevatedabnormallywasrespectively34.62%(18/52)and40.38%(21/52)innaturalcycleandCOScycle.18case
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