抽动障碍视频脑电图分析

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1、分类号：密级：UDC:编号：广州医学院硕士学位论文抽动障碍视频脑电图分析申请人：陈毅华导师：胡景鑫教授申请学位级别：医学硕士年级：二零零八级学科专业：病理与病理生理学研究方向：神经生理学论文提交日期：二0一二年五月论文答辩日期：二0一二年六月学位类型：医学科学学位学位授予单位：广州医学院答辩委员会主席：论文评阅人：二0一二年五月广州医学院硕士学位论文抽动障碍视频脑电图分析TheVideoEEGofTicDisorder申请人：陈毅华学号：2008261802年级：2008级专业：病理与病理生理学导师：胡景鑫教授广州医学院基础学院广州医学院·广州二0一二年五月目录中文摘要„„„„„„„„„„„„

2、„„„„„„„„„„„„1英文摘要„„„„„„„„„„„„„„„„„„„„„„„„2英文缩略词„„„„„„„„„„„„„„„„„„„„„„„3技术路线„„„„„„„„„„„„„„„„„„„„„„„„4前言„„„„„„„„„„„„„„„„„„„„„„„„7材料与方法„„„„„„„„„„„„„„„„„„„„„„„21结果„„„„„„„„„„„„„„„„„„„„„„„„23讨论„„„„„„„„„„„„„„„„„„„„„„„„27结论„„„„„„„„„„„„„„„„„„„„„„„„36参考文献„„„„„„„„„„„„„„„„„„„„„„„„37附图„„„„„„„„„„„„„„„„„„„„„„„„41综

3、述„„„„„„„„„„„„„„„„„„„„„„„„43已收录文章„„„„„„„„„„„„„„„„„„„„„„„59致谢„„„„„„„„„„„„„„„„„„„„„„„„54原创性声明„„„„„„„„„„„„„„„„„„„„„„„55广州医学院硕士学位论文抽动障碍视频脑电图分析抽动障碍视频脑电图分析专业：病理与病理生理学申请人：陈毅华导师：胡景鑫教授中文摘要研究背景：抽动障碍通常在儿童和青少年时期起病，主要表现为一个部位或多部位肌肉重复、快速、不自主的运动性抽动和（或）发声性抽动，并可伴有一些神经精神症状，比如多动行为、注意力不集中、强迫性动作和思维或其它行为症状。近年来随着家长和老师的重视，因抽

4、动症状明显、发作频繁而到儿童神经科门诊就诊的患者明显增多。在诊疗过程中，抽动障碍患者的临床表现往往存在单一、重复的特点，需与癫痫性抽搐鉴别。视频脑电图检查在此显得非常重要。现将对588例抽动障碍患者的视频脑电图作一分析探讨。目的：了解抽动障碍的视频脑电图改变。方法：对588例抽动障碍患者进行视频脑电图检查并分析其波形特征。结果：该组抽动障碍患者视频脑电图中，正常范围脑电图占97.79%，异常脑电图占2.21%。结论：抽动障碍患者的视频脑电图异常率并不高，而其中明确与癫痫相关的癫痫样的放电更是少数。抽动障碍与癫痫的鉴别必须通过临床表现与视频脑电图综合判断。关键词：抽动障碍，视频脑电图1广州医学院

5、硕士学位论文抽动障碍视频脑电图分析ThevideoEEGinTicDisorderMajor:PathologyandPathophysiologyPostgraduates:ChenYihuaSupervisor:HuJingxinprofessorDepartmentofPhysiologyABSTRACTBackground:TicDisordertypicallybegininchildhoodorteenage.Ticsareheteronomousrepeatingrapidnomalmovementsandvocalproductionsthatofteninvolveoneor

6、morethanonemusclegroup.AssociatedneuropsychiatricproblemssuchasOCD,ADHDlinktoit.Inrecentyears,parentsandteacherspaymoreattentionstoTD.Thenumberofpatientswhoaresenttothedoctorsforticsareobviousandfrequentincreaseobviously.BecauseticsarehardtodiagnosefromEP,VideoEEGisveryimportant.Objects:Toexaminethe

7、VideoEEGinTicDisorderpatients.Methods:1.Theclinicaldatawerecollectedfromcasefiles,includingname,sex,birthday,clinicalsymptoms.2.TheVideoEEGofTicDisorderpatients.Results:97.79%EEGsarenormal.2.21%areabn